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    Structural insight into unique features of the Translational apparatus in Plants 

    Mishra, Rishi Kumar
    Plants are constantly challenged with a variety of biotic and abiotic stress conditions. Being sessile, plants cannot evade these conditions. Most of these sudden changes in environmental conditions require a quick change ...

    Solution NMR studies of a potent subtilisin inhibitor from Budgett’s frog and the catalytic subunit of AHAS 

    Rami, Mihir
    This thesis involves a detailed structural study of two molecular systems, a small disulfide-rich peptide LL-TIL and a large catalytic subunit of AHAS. Subtilisin inhibitors play an important role in fighting against ...

    Structural and biochemical studies on mycobacterial Uracil-DNA glycosylase (Ung) and MutT1, key proteins involved in maintaining the genomic integrity in Mycobacteria 

    Raj, Prateek
    Maintaining genomic integrity is indispensable for the survival and propagation of an organism. Failure to do so can cause mutations involving structural and functional aberrations, leading to severe diseases. The causative ...

    Structural characterization of Staphylococcal γ-hemolysin in the presence of a lipid environment using single particle cryo-EM 

    Mishra, Suman
    γ-Hemolysin (γ-HL) is a quintessential bicomponent β-pore forming toxin (β-PFT) belonging to the arsenal of “superbug” Staphylococcus aureus. Here, we performed negative staining-TEM and single particle cryo-EM-based ...

    Insights into mRNA recruitment by eukaryotic initiation factor 4 during translation in Saccharomyces cerevisiae 

    Datey, Ayushi
    Ribosomes are responsible for synthesizing proteins in the cells by using mRNA as the template. However, the ribosomes cannot perform this function without the help of other protein factors. Different factors are required ...

    First thorough characterization of the structure, interactions and specificity of an archeal lectin with implication for TB infection 

    Sivaji, Nukathoti
    Decades long studies on plant lectins carried out in this laboratory have contributed substantially to glycobiology and helped in the initiation and development of macromolecular crystallography in India. Subsequently the ...

    Identification, characterization, structure, and assembly of type III toxin-antitoxin systems from Escherichia coli 

    Manikandan, P
    Bacteria adopt several defense strategies to enable their survival against the environmental threats they encounter from time to time. Toxin-antitoxin (TA) systems are being understood as a key bacterial defense mechanism ...

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    AuthorDatey, Ayushi (1)Manikandan, P (1)Mishra, Rishi Kumar (1)Mishra, Suman (1)Raj, Prateek (1)Rami, Mihir (1)Sivaji, Nukathoti (1)Subject
    NATURAL SCIENCES (7)
    Structural Biology (7)
    Cryo-EM (3)Ribosome (2)Bacteria (1)bacteria (1)Barley Yellow Dwarf Virus (1)Beta-prism I fold lectins (1)Biophysics (1)Cross-linking (1)... View MoreHas File(s)Yes (7)

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