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The Influence of Glycerol and Specific Genes on the Asymmetric Cell Division in Mycobacteria
The Influence of Glycerol and Specific Genes
on the Asymmetric Cell Division in Mycobacteria
Submitted by Atul Pradhan (S.R. No. 03-04-00-10-11-14-1-11678)
Background Information: Mycobacteria maintain heterogeneity in ...
Rv0805, a novel regulator of central carbon metabolism and cell envelope properties in mycobacteria
Metabolic flexibility is one of the key factors that underpin mycobacterial physiology and pathogenesis. During infection, mycobacteria shift towards utilising host-derived fatty acids, lipids, cholesterol and cholesterol-esters. ...
Mechanism of the Development of Genetic Resistance to Antibiotics Mediated by three Reactive Oxygen Species in Mycobacterium smegmatis
Bacteria use different means to survive in the continued presence of antibiotics. We find that upon prolonged exposure to antibiotics, mycobacteria put up a triphasic response comprised of a logarithmic reduction of the ...
Structural and biochemical studies on mycobacterial Uracil-DNA glycosylase (Ung) and MutT1, key proteins involved in maintaining the genomic integrity in Mycobacteria
Maintaining genomic integrity is indispensable for the survival and propagation of an organism. Failure to do so can cause mutations involving structural and functional aberrations, leading to severe diseases. The causative ...