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Studies on NMPylase and Valine Catabolism Enzymes from Mycobacterium
Post-translational modifications constitute an important arm of the regulatory mechanism in mammalian cells. Therefore, bacterial pathogens, which thrive by mimicking the host cell signaling, are proving to be difficult ...
Structure-Function Analysis of Focal Adhesion Protein Vinculin in Neocortical Axon Growth and Development
Axon growth and extension are dependent on the interaction of neurons with extracellular matrix (ECM). The interaction between cells and ECM is known as focal adhesion (FA). Vinculin is one the major proteins of FA complex ...
Division of the Salmonella Containing Vacuole and Other Virulence Strategies Employed by Salmonella
Salmonella comprises a genus of rod-shaped, Gram-negative, non-sporulating and primarily motile enterobacteria. They have remained a major cause of morbidity and mortality worldwide, claiming several hundreds of lives per ...
Intrasexual competition in females of a socially polygynous lizard, Psammophilus dorsalis
Competition between individuals of the same sex, intrasexual competition, has received much attention in males, mainly because such competition, which is primarily for mates (i.e. sexual selection), often selects for ...
Insights into the Regulation of Transcription Initiation of DNA Gyrase and Role of Transcription Factor Gre from Mycobacterium tuberculosis
Genus Mycobacterium comprises a large number of species including many pathogens such as Mycobacterium leprae, Mycobacterium abscessus and Mycobacterium tuberculosis (Mtb), the last one is the causative agent of the fatal ...
Response of Mycobacterium tuberculosis to Hypoxia and its physiological Significance - A Morphological and Molecular Level Study
Mycobacterium tuberculosis (Mtb) has evolved as an important clinical pathogen due to its ability to gain multidrug resistance, to enter into latency to persist there and to get reactivated from the latent infection in ...
Dynamic colour change in Psammophilus dorsalis: role of natural and sexual selection
Overall, the results from this study support the idea that animal signals arise from a balance between increased conspicuousness for social signalling and inconspicuousness to avoid predation risk. Animals that can change ...
An integrative analysis of Cell Adhesion Molecules (CAMs) in Glioma: The Essential role of PTGFRN and ASTN1 in Glioma and Glioma Stem-like Cells
The central nervous system tissue contains neural stem cells which differentiate and give rise to the neurons and glial cells. The glial cells maintain neurons by providing nutrients, physical support and protection. Unlike ...
Super-Resolution Imaging Reveals Localization and Regulation of Nanoscale Machinery Involved in the Amyloidogenic Pathway
Amyloid Precursor Protein (APP) is a key player in Alzheimer’s disease (AD). Despite
intuitive insights into differential proteolysis of APP, there is a little understanding of how the
amyloidogenic machinery is distributed ...
Intrinsic Noise in Collective Dynamics
Animal groups exhibit many emergent properties that are a consequence of local interactions.
Linking individual-level behaviour to group-level dynamics has been a question
of fundamental interest from both biological and ...