Search
Now showing items 741-750 of 1025
Lineage delimitation and diversification in Nyctibatrachus, an endemic frog genus from the Western Ghats
Determining how biodiversity is produced and maintained remains one of the fundamental
questions in ecology. The phenomenon of diversification, which occurs via the interplay of
speciation and extinction, holds the key ...
Mechanism of β-catenin regulation by IGFBP2: Role in Glioblastoma progression
Insulin-like growth factor binding proteins (IGFBPs) were initially identified as high affinity binders of Insulin-like growth factors (IGFs). There are six IGFBPs which regulate the bioavailability and functions of IGFs ...
Mapping the Functional Domain of Glycodelin A : An Immunomodulatory Lipocalin
Glycodelins (Gds) are dimeric, glycosylated proteins belonging to the lipocalin superfamily which are primarily transporters of small hydrophobic molecules. Gd is classified under the lipocalin superfamily as it shows 55 ...
Understanding the Regulation of mRNA Translation Repression by RGG-motif Proteins
Messenger RNA translation is one of the most energy expensive steps in the process of gene expression and therefore translation regulation is critical for maintaining cellular homeostasis. In contrast to transcriptional ...
Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions
Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, ...
Distribution, activity budget and feeding ecology of Himalayan gray langur (Semnopithecus ajax) in Kashmir Himalaya
Colobines are group of primates known to inhabit harsh environments. These habitats pose different challenges which they have coped up physiologically and behaviourally. Primates in such environments are subjected to ...
Molecular Characterization of Mannose Binding Lectins
Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ...
Mechanistic and Functional Insights into Mycobacterium bovis BCG Triggered PRR Signaling : Implications for Immune Subversion Strategies
Pathogenic mycobacteria are among the most dreadful pathogens known to mankind as one third of the world’s population is latently infected with M. tuberculosis, the causative agent of pulmonary tuberculosis. Host immune ...
Oleosin, a Bifunctional Enzyme is Phosphoregulated by a Protein Kinase
In eukaryotic cells, lipids are indispensable principal components that vitiate biological
life. Lipids are classified into two major groups, polar and non-polar lipids. Polar lipids
are phospholipids, whereas non-polar ...
Transcriptional Regulation of Fatty Acid Transport by Sirtuin 2
The heart is a highly dynamic organ and under normal physiological conditions, it is heavily dependent on fatty acid oxidation to meet its energy requirements (Abumrad and Goldberg 2016). Fatty acid transport is a crucial ...