Search
Now showing items 541-550 of 1025
Regulation Of Interferon Regulatory Factor-2 mRNA Translation By 'IRES' Element : Possible Role Of trans Acting Factors
(2009-09-03)
Cellular response to various stress conditions involves regulation of gene expression by different mechanisms. Translation is the final step in the flow of genetic information and regulation at this level allows an early ...
Lip Y, The PE Family Triacylglycerol Hydrolase From Mycobacterium Tuberculosis : Functional Role Of The PE Domain And Immunogenicity
(2010-10-28)
More human lives have been lost to tuberculosis than to any other disease and despite the availability of effective short course chemotherapy (DOTS) as well as the Bacilli Calmette Guerin (BCG) vaccine, tuberculosis continues ...
Role Of Idiotypic Anti-Idiotypic Network In The Sustenance Of Immunological Memory
(2009-05-25)
Living amidst a milieu of pathogenic organisms, vertebrates are in constant threat of contracting one or the other disease. As a mechanism of protection against such ‘invasions’, the vertebrate immune system has evolved ...
Studies On Saccharomyces Cerevisiae RNA Polymerase II Subunit Rpb7 And Its Eukaryotic Orthologs
(2010-06-03)
Saccharomyces cerevisiae is an excellent experimental model organism to study various biological processes owing to its versatile genetics, biochemistry, and standard laboratory conditions. S. cerevisiae shows distinct ...
Survival Strategies Of SALMONELLA
(2010-08-25)
The genus Salmonella includes facultative intracellular pathogens. Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever in humans killing about 2,00,000 people globally every year. Salmonella enterica serovars ...
Survival Strategies Of Salmonella Under Host Nitrosative Stress And Its Role In Pathogenesis
(2010-12-07)
Chapter: 1
Introduction
Genus Salmonella is a Gram-negative rod shaped facultative anaerobic bacteria that can survive inside the host macrophages and cause persistent infection. Salmonella Typhimurium, Salmonella Typhi ...
Studies On DNA Gyrase From Mycobacteria : Insights Into Its Mechanism Of Action And Elucidation Of Its Interaction With The Transcription Machinery
(2010-09-30)
Packaging of genomic DNA by proteins and super coiling into chromatin and chromatin-like structures (in bacteria) influences nearly all nuclear process such as replication, transcription, repair, and recombination. A ...
Processing Of DNA Recombination And Replication Intermediates By Mycobacterium Tuberculosis RuvA And RuvB Proteins
(2013-06-14)
Homologous recombination (HR) is a highly conserved cellular process involved in the
maintenance of chromosomal integrity and generation of genetic diversity. Biochemical and genetic studies have suggested that HR is ...
Production Of Anticancer Drug Taxol And Its Precursor Baccatin III By Fusarium Solani And Their Apoptotic Activity On Human Cancer Cell Lines
(2013-06-24)
Taxol (generic name paclitaxel), a plant‐derived antineoplastic agent, was
originally isolated from the bark of the Pacific yew, Taxus brevifolia. Obtaining
taxol from this source requires destruction of trees. It has ...
Helicobacter Pylori Restriction-Modification Systems : Possible Roles Beyond Genome Protection
(2013-06-06)
Helicobacter pylori is one of the most potential and successful human pathogen which colonizes atleast 50% of world population. One of the important characteristics of this pathogen is the degree of allelic diversity and ...