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Insights Into The Mechanistic Details Of The M.Tuberculosis Pantothenate Kinase : The Key Regulatory Enzyme Of CoA Biosynthesis
(2013-04-26)
Tuberculosis (TB), caused by Mycobacterium tuberculosis, has long been the scourge of humanity, claiming millions of lives. It is the most devastating infectious disease of the world in terms of mortality as well as morbidity ...
Crystal Structure Of Jacalin At 3.0A Resolution
(2012-11-15)
How Much Initiator tRNA Does Escherichia Coli Need?
(2017-11-27)
The work discussed in this thesis deals with the significance of initiator tRNA gene copy number in Escherichia coli. A summary of the relevant literature discussing the process of protein synthesis, ...
Interaction Of Chaperone SecB With Protein Substrates: A Biophysical Study
(Indian Institute of Science, 2006-10-17)
In the cell, as in in vitro, the final conformation of a protein is determined by it's amino acid sequence (1). Some isolated proteins can be denatured and refolded in vitro in absence of extrinsic factors. However, in ...
Unique Response and the Survival Mechanism of Mycobacterial Subpopulations against Oxidative and Nitrite Stress
(2017-12-03)
Mycobacterial populations are known for the heterogeneity in terms of cell size, morphology, and metabolic status, which are believed to help the population survive under stress conditions. Such population heterogeneity ...
Identification, Structural and Functional Characterisation of the Molecule that Induces Asymmetric Cell Division in Mycobacteria
(2017-12-03)
Phenotypic heterogeneity in terms of cell size, morphology, and metabolic status, which are believed to help the population survive under stress conditions, is known in mycobacterial populations. Such population heterogeneity ...
Regulation of Leaf Margin Development by TOOTH/MIR160A in Arabidopsis Thaliana
(2017-11-13)
TOOTH/MIR160A regulates leaf margin outgrowth in Arabidopsis thaliana
Unlike animals, a striking aspect of the plant development is that they have evolved a flexible pattern of post embryonic development. This exposes ...
The Role of Initiation Factor 3 : Insights from E. Coli, Mitochondria and Mycoplasma
(2018-01-07)
The process of translation initiation is the most highly regulated step of protein synthesis. In bacteria, three initiation factors (IF1, IF2 and IF3) play crucial roles during initiation. IF3 acts as an anti-association ...
Functional Characterization of Saccharomyces Cerevisiae SUB1 in Starvation Induced Sporulation Response
(2017-12-12)
Among the various external signals perceived by yeast cells, nutrient availability is a condition to which these cells show a highly diverse biological response. Diploid cells in response to different nutritional stress ...
Role of SIRT6 in Myofibroblast Cell Death
(2018-01-10)
Cardiovascular diseases are one of the leading causes of mortality. A common denominator across most of the cardiovascular diseases like diabetic cardiomyopathy, hypertrophic cardiomyopathy, myocardial infarction and dilated ...