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Understanding the Role of ZCF32, a Zinc Cluster Transcription Factor, in Candida albicans Biology
(2018-05-25)
As a human fungal pathogen, Candida albicans can cause a wide variety of disease conditions ranging from superficial to systemic infections. Many of these infections are caused by an inherent ability of the pathogen to ...
Physiological Role of Folate Dehydrogenase in One Carbon Metabolism of Escherichia Coli
(2018-06-08)
Thesis addresses the physiological role of formyl tetrahydrofolate synthetase (Fhs) and bifunctional folate dehydrogenase (FolD) in folate mediated one carbon metabolism in bacteria. Thesis consists of 5 chapters. First ...
Structural, Functional And Transcriptional Analysis Of Nucleoside Diphosphate Kinase From Mycobacterium Smegmatis mc2 155
(2011-08-05)
Maintenance of the levels of nucleoside triphosphates (NTPs) as well as their corresponding deoxy derivatives (dNTPs) is crucial to all growth and developmental processes. The enzyme nucleoside diphosphate kinase (NDK) ...
Functional Characterization Of The Internal Ribosome Entry Site Of Coxsackievirus B3 RNA
(2011-07-11)
CoxsackievirusB3 (CVB3), a member of the Picornaviridae family is the causative agent of Virus-induced Myocarditis and Dilated Cardiomyopathy. The 5’UTR contains an Internal Ribosome Entry Site or IRES element that recruits ...