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Biogeography and comparative phylogeography of freshwater snails of India
Distribution of flora and fauna is shaped by both current and historical processes. In my thesis
I concentrated on how the historical component of the governing processes have dictated the
current distribution of biota. ...
Use of sub-family specific residues of protein modules in recognizing sites of functional and structural specialization
Functional and regulatory features of a protein in a living system are determined by several factors
such as chemical nature and three-dimensional arrangement of residues in the functional site, spatial
and temporal ...
The role of Rv1860 from M. tuberculosis in modulating the host immune response
Tuberculosis continues to prevail as the major cause of mortality from any single pathogen around the world, despite implementation of control programs and the availability of effective drugs and the vaccine BCG. Mycobacterium ...
Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development
Title: Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development
The classic ABCDE model for floral organ identity show that ...
Comparative evaluation of retrograde regulatory proteins (Rtg1p, Rtg2p, and Rtg3p) of Saccharomyces cerevisiae and Pichia pastoris and identification of P. pastoris RtgXp as a novel regulator of multiple metabolic pathways
Our work demonstrates for the first time that PpRtgXp, a basic, helix-loop-helix (bHLH) protein, is a global regulator of carbon metabolism. PpRtgXp constitutively localizes inside the nucleus. Despite lacking the C-terminal ...
Use of strategically designed protein-like sequences in structure and function recognition
The advent of high fidelity protein sequencing techniques has led to a considerable wealth
of sequence data. However, the number of proteins with information on 3-D structure and
functional features available is considerably ...
Computational studies on interacting proteins with special reference to toxin-antitoxin systems
Proteins interact with other proteins to maintain functional homeostasis of the cell by tightly regulating cellular processes. Hence, it becomes important to understand not only the downstream effects of protein-protein ...
Investigating the mechanisms of cancer drug resistance
Clinical chemo-resistance has posed a challenge to scientists and clinicians since the development of chemotherapeutics as anticancer strategy. Mechanisms of drug resistance continue to be a subject investigation amongst ...
A Phylogenetic Perspective on The Phytogeography of Western Ghats
I used a finer scale data of 156 published plots across the entire latitudinal range of WG, covering most of the protected
forests. The pruned phylogeny for this study consisted of 367 species, of which ~ 50% are taxa
endemic ...
Condition-dependent signalling and mating behaviour in the tree cricket, Oecanthus henryi
Male reproductive success in systems exhibiting sexually selected traits can be driven by male mating effort in sexual signals and in the production of nuptial gifts. Male mating effort can be determined by various biotic ...