Stop codon readthrough is the process in which translation continues beyond a stop codon till a downstream, in-frame stop codon generating a polypeptide with a C-terminal extension. MTCH2 was selected as a potential ...

Microorganisms are the unseen majority that determines ecosystem processes, they perform biogeochemical functions that translate into essential services, and regulate global climate. In grazing ecosystems, which represent ...

During translation, the message encoded in mRNAs is decoded by ribosomes to synthesize proteins following strict canonical decoding rules. This process is tightly regulated and several mechanisms exist in cells that ensure ...

Mitochondria are essential eukaryotic organelles required for diverse cellular functions including, energy homeostasis, iron-sulfur cluster biogenesis, and signaling. Therefore, the maintenance of organelle quality control ...

Insertion of  amino acid residues into all  polypeptide backbones leads to an expanded repertoire of secondary structures. In the present thesis an attempt has been made to explore the conformational properties of the  ...

Glycodelins (Gds) are dimeric, glycosylated proteins belonging to the lipocalin superfamily which are primarily transporters of small hydrophobic molecules. Gd is classified under the lipocalin superfamily as it shows 55 ...

In eukaryotic cells, lipids are indispensable principal components that vitiate biological life. Lipids are classified into two major groups, polar and non-polar lipids. Polar lipids are phospholipids, whereas non-polar ...

A number of studies have established that DNA targeting is a successful strategy in anticancer therapy. In recent years, however, the focus has shifted from double-stranded DNA to alternative DNA motifs such as G-quadruplex ...

In a healthy cell, the ROS levels are stringently regulated by the action of various enzymatic or non-enzymatic antioxidant systems. Imbalance in the ROS homeostasis generates oxidative stress resulting in damage to cellular ...

Viruses are major pathogenic agents that cause a variety of diseases in all living systems. Since their first isolation in 1892 by Dimitrii Ivanovsky, methods of their diagnosis and control, their life cycles, host - virus ...