Now showing items 11-20 of 51
Structural Studies Of Mycobacterial Uracil-DNA Glycosylase (Ung) And Single-Stranded DNA Binding Protein (SSB)
(2011-09-21)
For survival and successful propagation, every organism has to maintain the genomic integrity of the cell. The information content, in the form of nucleotide bases, is constantly threatened by endogenous agents and ...
Structure-Function Correlations In Aminoacyl tRNA Synthetases Through The Dynamics Of Structure Network
(2010-08-16)
Aminoacyl-tRNA synthetases (aaRSs) are at the center of the question of the origin of life and are essential proteins found in all living organisms. AARSs arose early in evolution to interpret genetic code and are believed ...
Functional Analysis Of Unique Motifs In Dimeric EcoP151 DNA Methyltransferase
(2011-01-11)
Restriction endonucleases occur ubiquitously among bacteria, archaea and in viruses of certain unicellular algae, and they are usually accompanied by a modification enzyme of identical specificity; together, the two ...
Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution
(2010-09-30)
Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ...
Molecular Genetic Analysis Of The Role Of Nse2, A SUMO E3 Ligase Of The Smc5/6 Complex, In Resisting Genotoxic Stress And Maintaining Chromosome Stability In Saccharomyces Cerevisiae
(2011-01-20)
DNA repair pathways have evolved to protect the genome from damage caused by intrinsic and extrinsic factors. Although numerous DNA repair mechanisms have been studied and reported, information regarding how they coordinate ...