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Structural Studies On Three-Fold Symmetric Plant Lectins
(2013-05-21)
Lectins, multivalent carbohydrate-binding proteins of non-immune origin, have the unique ability to decode the information contained in complex carbohydrate structures of glycoproteins and glycolipids by stereo-specifically ...
Structural And Mechanistic Studies On Receptor Protein Tyrosine Phosphatases From Drosophila Melanogaster
(2013-06-20)
Protein Tyrosine Phosphatases (PTPs) initiate, modulate and terminate key cellular processes by dephosphorylating phosphotyrosine (pY) residues on signaling proteins. The coordinated action of PTPs with their cognate ...
Sequence Analysis And Design Of Immunogens From The Stem Domain Of Influenza Hemagglutinin
(2013-07-10)
Influenza is an important respiratory pathogen that infects several million people each year. Currently available flu vaccines have to be updated regularly in order to be effective as the virus changes its composition by ...
Structural Studies On Physalis Mottle Virus Capsid Proteins & Stress Response Proteins Of Oryza Sativa And Salmonella Typhimurium
(2013-04-26)
X-ray crystallography is one of the most powerful tools for the elucidation of the structure of biological macromolecules such as proteins and viruses. Crystallographic techniques are extensively used for investigations ...
Mechanistic And Regulatory Aspects Of The Mycobacterium Tuberculosis Dephosphocoenzyme A Kinase
(2013-09-11)
The current, grim world-TB scenario, with TB being the single largest infectious disease
killer, warrants a more effective approach to tackle the deadly pathogen, Mycobacterium
tuberculosis. The deadly synergy of this ...
Computer Modelling Studies On DNA Triple Helices
(2013-07-22)
Conformational Analysis And Design Of Disulfides In Antiparallel β-Sheets And Helices
(2013-08-30)
Disulfides are the primary covalent interactions within a protein molecule that connect residues which are sequentially distant. Naturally occurring disulfides enhance the stability of the protein by destabilization of ...
Biochemical Characterization Of Heat Shock Protein 90 From Plasmodium Falciparum
(2013-06-07)
Molecular chaperones are a group of proteins which maintain cellular homeostasis by assisting de novo protein folding and their refolding to native state after destabilization due to external stress. They are also known ...