Search
Now showing items 41-50 of 55
Delineation Of Signal Transduction Events During The Induction Of SOCS3 By Mycobacterium Bovis BCG : Possible Implications For Immune Subversion Mechanisms
(2010-09-30)
Pathogenic Mycobacteria are among the most unrelenting pathogens known to mankind as one-third of the world population is latently infected with Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis. ...
Translational Control Of p53 And Its Isoform By Internal Initiation
(2010-07-19)
Tumor suppressor p53, the guardian of the genome, has been intensely studied molecule owing to its central role in maintaining cellular integrity. While the level of p53 protein is maintained low in unstressed conditions, ...
Functional Analysis Of DdRpb4 And DdRpb7, Two Subunits Of Dictyostelium Discoideum RNA Polymerase II
(2010-04-06)
The process of eukaryotic transcription and its regulation has been an interesting area of research for decades. With more insights into the process of transcriptional regulation of genes, studies have revealed a ...
Cell Survival Strategies : Role Of Gyrase Modulatory Proteins
(2010-07-21)
A steady state level of negative supercoiling is essential for chromosome condensation, initiation of replication and subsequent elongation step. DNA gyrase, found in every eubacteria, serves the essential housekeeping ...
Elucidation Of Differential Role Of A Subunit Of RNA Polymerase II, Rpb4 In General And Stress Responsive Transcription In Saccharomyces Cerevisiae
(2010-09-14)
RNA polymerase II (Pol II) is the enzyme responsible for the synthesis of all mRNAs in eukaryotic cells. As the central component of the eukaryotic transcription machinery, Pol II is the final target of regulatory pathways. ...
Lip Y, The PE Family Triacylglycerol Hydrolase From Mycobacterium Tuberculosis : Functional Role Of The PE Domain And Immunogenicity
(2010-10-28)
More human lives have been lost to tuberculosis than to any other disease and despite the availability of effective short course chemotherapy (DOTS) as well as the Bacilli Calmette Guerin (BCG) vaccine, tuberculosis continues ...
Studies On Saccharomyces Cerevisiae RNA Polymerase II Subunit Rpb7 And Its Eukaryotic Orthologs
(2010-06-03)
Saccharomyces cerevisiae is an excellent experimental model organism to study various biological processes owing to its versatile genetics, biochemistry, and standard laboratory conditions. S. cerevisiae shows distinct ...
Survival Strategies Of SALMONELLA
(2010-08-25)
The genus Salmonella includes facultative intracellular pathogens. Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever in humans killing about 2,00,000 people globally every year. Salmonella enterica serovars ...
Survival Strategies Of Salmonella Under Host Nitrosative Stress And Its Role In Pathogenesis
(2010-12-07)
Chapter: 1
Introduction
Genus Salmonella is a Gram-negative rod shaped facultative anaerobic bacteria that can survive inside the host macrophages and cause persistent infection. Salmonella Typhimurium, Salmonella Typhi ...
Studies On DNA Gyrase From Mycobacteria : Insights Into Its Mechanism Of Action And Elucidation Of Its Interaction With The Transcription Machinery
(2010-09-30)
Packaging of genomic DNA by proteins and super coiling into chromatin and chromatin-like structures (in bacteria) influences nearly all nuclear process such as replication, transcription, repair, and recombination. A ...