Browsing Division of Biological Sciences by Subject "Topoisomerase"
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Mycobacterial topoisomerases: insights into structure, mechanism and function
DNA encounters topological constraints during essential cellular processes such as replication, transcription, and chromosome segregation. To ensure facile execution of these processes, a ubiquitous class of enzymes known ... -
Mycobacterium smegmatis topoisomerase I : insights into site specific recognition and mechanism of action
Mycobacterium smegmatis TOPOISOMERASE I: INSIGHTS INTO SITE-SPECIFIC RECOGNITION AND MECHANISM OF ACTION The work embodied in this thesis is an attempt to understand the relaxation mechanism catalyzed by Mycobacterium ...