Browsing Division of Biological Sciences by Subject "OneCarbon Metabolism"
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Mechanism of interaction of carbonyl-directed reagents at the active site of sheep liver serine hydroxymethyltransferase
SHMT catalyzes the first step in the pathway for the interconversion of folate coenzymes. In this reaction, Ser is converted to Gly and the hydroxymethyl group of Ser is transferred to Hfolate to yield 5,10CHHfolate. SHMT ...