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    Browsing Division of Biological Sciences by Subject "Lactate"

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      • Ischemic Concentrations of Lactate Increase TREK1 Channel Activity and Expression 

        Ghatak, Swagata
        TREK1 is a two-pore domain leak potassium channel which contributes to resting membrane potential. TREK1-/- mice exhibit increased neuronal mortality after global ischemia. Neuroprotective agents like volatile anesthetics ...
      • Role of Lactate and TREK1 Channels in Neuroprotection during Cerebral Ischemia – in Vitro Study in Rat Hippocampus 

        Banerjee, Aditi (2017-12-16)
        Cerebral ischemia is a highly debilitating condition where shortage of oxygen and glucose leads to profuse cell death. Insufficient blood supply to the brain leads to cerebral ischemia and increase in extracellular lactate ...

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