Browsing Division of Biological Sciences by Subject "Glioma"
Now showing items 1-8 of 8
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Deciphering the Role of METTL3-Dependent m6A-epitranscriptome in Glioma Stem-like Cells
The major roadblocks in treatment for GBM are resistance to therapy and recurrence of GBM cells. Regardless of various treatment strategies, the average survival of GBM patients is poor and incidence of recurrence remains ... -
Decoding Epigenetic Regulators in Cancer: Acetylation of HIF2A by Histone Acetyltransferase 1 (HAT1) is essential for executing hypoxia response in glioma
Gliomas are tumors of the central nervous system arising from glial cells. Based on the origin of the cell type, it can be astrocytoma, oligodendroglioma, and ependymoma. Astrocytoma is the most common type of glioma, ... -
DNA Methylation Landscape of Astrocytoma : Role of Fibromodulin (FMOD), a Hypomethylated and Upregulated Gene, in Glioblastoma Cell Migration
(2018-08-30)Astrocytoma is defined as the neoplasia of astrocytes, the most abundant non-neuronal glial cells in brain. According to the WHO classification, the different grades of astrocytoma are- gradeI/pilocytic astrocytoma (benign ... -
Elucidating Deregulated Novel Pathways in Glioma through Genetic and Epigenetic Approaches
Malignancy of glial cells is termed as glioma. Gliomas comprise of thirty percent of all tumors of the central nervous system (CNS) and eighty percent of malignant brain tumors (Goodenberger and Jenkins, 2012). Astrocytoma, ... -
Epigenetic Modulators of Glioma : From miRNAs to Chromatin Modifiers
(2018-02-20)The glial cells of the brain and the peripheral nervous system retain the capacity to divide and proliferate throughout the lifespan of an individual and thereby have the propensity to give rise to the most adult neurological ... -
Genetics of Glioma : Transcriptome and MiRNome Based Approches
(2018-03-26)Glioma, the tumor of glial cells, is one of the common types of primary central nervous system (CNS) neoplasms. Astrocytoma is the most common of all gliomas and originates from astrocytic glial cells. Astrocytoma tumors ... -
Proteomic Approaches to Study Glioma Development, Progression and Therapy
(2018-04-02)Astrocytoma, the tumor of astrocytic origin, accounts for about 60 % of the primary brain tumors. As per World Health Organization grading system, astrocytoma is classified as circumscribed astrocytoma (Grade I; pilocytic ... -
Proteomics-based Identification of Serum Biomarkers : Role of Secreted MCSF and CRP in Glioma Pathogenesis
Gliomas are the neoplasia of glial cells present in the brain and comprises of more than 70% of all the neoplasms of the central nervous system. They consist of a family of primary brain tumors that are categorized based ...