Browsing Division of Biological Sciences by Subject "Biochemical Genetics"
Now showing items 1-20 of 63
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Biochemical And Functional Characterization Of Evolutionarily Conserved Metallophosphoesterases The 239FB/AB Family
(2010-12-30)With the advent of large scale genome sequencing efforts along with more sophisticated methods of genetic mapping, a number of loci have been identified that are associated with human diseases. Intriguingly, many genes ... -
Biochemical Characterization Of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 Using Telomeric DNA : A Role For The Endonucleolytic Activity Of Mre11 In Telomere Length Maintenance And Its Regulation By Rad50
(2009-05-15)Meiotic recombination is a prerequisite for exchange of genetic information in all Sexually reproducing organisms. This process is initiated by the formation of double stranded breaks (DSBs) in DNA followed by homology ... -
Breast Cancer Susceptibility Gene 1 (BRCA1) And Breast Cancer
(2009-04-15)Breast Cancer susceptibility gene 1 (BRCA1) & Breast Cancer Breast cancer is one of the most common malignancies affecting women worldwide. About 5-10% of all cases are estimated to be familial. Mutations in the BRCA1 ... -
Cell Surface Of Mycobacterium Smegmatis At The Stationary Phase : Regulation Of Gene Expression
(2009-05-21)Tuberculosis remains one of the oldest diseases known to mankind but still persists as a very major risk. Discovery of several antimycobacterials was marked by a steady decline in the active cases of pulmonary tuberculosis. ... -
Cyclic AMP-Regulated Protein Lysine Acetylation In Mycobacteria
(2015-07-17)Tuberculosis continues to be one of the major causes of morbidity and mortality worldwide. Several mycobacterial species such as M. tuberculosis and M. africanum are responsible for causing this disease in humans. Reports ... -
Differential Regulation Of tRNA1 Gly Genes In Bombyx Mori
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DNA Repair In Mycobacteria
(2013-08-13) -
Elucidation Of Differential Role Of A Subunit Of RNA Polymerase II, Rpb4 In General And Stress Responsive Transcription In Saccharomyces Cerevisiae
(2010-09-14)RNA polymerase II (Pol II) is the enzyme responsible for the synthesis of all mRNAs in eukaryotic cells. As the central component of the eukaryotic transcription machinery, Pol II is the final target of regulatory pathways. ... -
Epigenetic Regulators Of Development In The Social Amoeba Dictyostellium Discoideum : The Roles Played By Histone Deacetylases And Heat Shock Protein 90
(2011-01-20)The major evolutionary transition from single-celled to multicellular life is believed to have occurred independently of the main metazoan lineages in the cellular slime moulds, of which Dictyostelium discoideum is the ... -
Exploring Protein-Nucleic Acid Interactions Using Graph And Network Approaches
(2009-09-22)The flow of genetic information from genes to proteins is mediated through proteins which interact with the nucleic acids at several stages to successfully transmit the information from the nucleus to the cell cytoplasm. ... -
Expression Profiling Of Genes Regulated By TGF-β : Role Of Multiple Signaling Pathways
(2009-05-12)Transforming growth factor-β (TGF-β) is the proto-type member of a super family of secreted proteins comprised of several structurally related, but functionally divergent proteins like the BMP, activin, inhibin, mullerian ... -
Functional Analysis Of AtCAP Genes In Arabidopsis Thaliana
(2013-08-14) -
Functional Analysis Of DdRpb4 And DdRpb7, Two Subunits Of Dictyostelium Discoideum RNA Polymerase II
(2010-04-06)The process of eukaryotic transcription and its regulation has been an interesting area of research for decades. With more insights into the process of transcriptional regulation of genes, studies have revealed a ... -
Functional Analysis Of Unique Motifs In Dimeric EcoP151 DNA Methyltransferase
(2011-01-11)Restriction endonucleases occur ubiquitously among bacteria, archaea and in viruses of certain unicellular algae, and they are usually accompanied by a modification enzyme of identical specificity; together, the two ... -
Functional Characterization And Regulation Of UvrD Helicases From Haemophilus Influenzae And Helicobacter Pylori, And Recj Exonuclease Fron Haemophilus Influenzae
(2013-04-01)DNA repair processes are crucial for mutation avoidance and the maintenance of genetic integrity in all organisms. Organisms rely on repair processes to combat genotoxic stress imposed by hostile host environment, and ... -
Functional Characterization Of The Internal Ribosome Entry Site Of Coxsackievirus B3 RNA
(2011-07-11)CoxsackievirusB3 (CVB3), a member of the Picornaviridae family is the causative agent of Virus-induced Myocarditis and Dilated Cardiomyopathy. The 5’UTR contains an Internal Ribosome Entry Site or IRES element that recruits ...