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    Browsing Division of Biological Sciences by Advisor "Sundaresan, N Ravi"

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      • Role of Sirt2 in Stress-induced Muscle Atrophy 

        Tamta, Ankit Kumar
        Skeletal muscle is one of the essential organs in our body, responsible for various functions such as locomotion, transport, protein storage, and thermoregulation. Under certain pathological conditions, there is a reduction ...
      • Role of SIRT6 in Myofibroblast Cell Death 

        Subramanian, Veena (2018-01-10)
        Cardiovascular diseases are one of the leading causes of mortality. A common denominator across most of the cardiovascular diseases like diabetic cardiomyopathy, hypertrophic cardiomyopathy, myocardial infarction and dilated ...
      • Role of SIRT6 in the Regulation of Glucose Metabolism and Fatty Acid Uptake in Heart 

        Khan, Danish
        The adult heart heavily relies on fatty acid for most of its energy supplies. The heart derives most of the fatty acid from circulation. Hence, fatty acid uptake forms a crucial step in cardiac metabolism. Studies have ...
      • Role of Sirtuin 2 in the development of tissue fibrosis 

        Kumar, Shweta
        Wound healing is a crucial physiological process required for the healthy lifespan of an organism. Dysregulation in the process of wound healing leads to the production of excess extracellular matrix leading to fibrosis. ...
      • Role of Sirtuin6 in the maintenance of cardiac lysosomal homeostasis 

        Raghu, Sukanya
        The response to cardiac stress can be divided into two phases- an initial adaptive compensatory phase followed by a maladaptive decompensatory phase. Protein homeostasis in cardiomyocytes has been observed to behave ...
      • Transcriptional Regulation of Fatty Acid Transport by Sirtuin 2 

        Chaudhuri, Riddhi
        The heart is a highly dynamic organ and under normal physiological conditions, it is heavily dependent on fatty acid oxidation to meet its energy requirements (Abumrad and Goldberg 2016). Fatty acid transport is a crucial ...
      • Understanding the Role of SIRT2 in Cardiac Hypertrophy, Cell Death and Glucose Homeostasis 

        Sarikhani, Mohsen
        Over the last century the major causes of human deaths and ailments has shifted from acute infectious diseases to chronic aging related disorders like cancer and type-2 diabetes. The aging process is a universal property ...

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