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    • Browsing Division of Biological Sciences by Advisor
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    Browsing Division of Biological Sciences by Advisor "Kotak, Sachin"

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      • Dissecting the function of NuMA in cleavage furrow formation and chromatin decondensation at the mitotic exit in animal cells 

        Rajeevan, Ashwathi
        In animal cells, the duplicated genetic material is aligned on a microtubule-based structure known as the mitotic spindle during mitosis. At the mitotic exit, the mitotic spindle elongates, and the sister chromatids get ...
      • PP2A-phosphatase and Polo-like kinase 1 regulates spindle positioning by orchestrating the cortical levels of the dynein adaptor NuMA 

        Keshri, Riya
        The mitotic spindle is a microtubule-based diamond shape structure that captures chromosomes and facilitates their segregation during anaphase. Proper positioning of the mitotic spindle is critical for defining the ...
      • Understanding the mechanisms of polarity establishment and nuclear envelope breakdown in Caenorhabditis elegans embryos 

        Kapoor, Sukriti
        Polarity establishment is critical for the development and stem cell lineages. The one-cell stage of the Caenorhabditis elegans embryo polarizes soon after fertilization. As a result, the first division of the embryo ...
      • Unravelling the spindle-independent function of cortical force-generating machinery (LIN-5/GPR-1/2) during cleavage furrow formation and abscission in C. elegans embryos 

        Adhikary, Kuheli
        Cytokinesis marks the final stage of cell division, where a single mother cell divides into two daughter cells. This intricate process begins with the assembly of an actomyosin-based cleavage furrow at the equatorial ...

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