Browsing Division of Biological Sciences by Subject "Biochemistry"
Now showing items 161-180 of 204
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Structure-Function Correlative Studies On The Biochemical Properties (Polymerisation, GTP binding, GTPase) Of Mycobacterial Cytokinetic Protein FtsZ In Vitro
(2010-03-26)FtsZ, the principal cell-division protein, polymerizes in GTP-dependent manner in vitro (Bramhill and Thompson, 1994; Mukherjee and Lutkenhaus, 1994; Rivas et al., 2000). FtsZ polymerization at the mid-cell site of bacterium ... -
Structure-Function Relationships of Saccharomyces Cerevisiae Meiosis Specific Hop 1 Protein : Implications for Chromosome Condensation, Pairing and Spore Formation
(2018-03-07)Meiosis is a specialized type of cell division essential for the production of four normal haploid gametes. In early prophase I of meiosis, the intimate synapsis between homologous chromosomes, and the formation of chiasmata, ... -
Studies On Cloning And Characterization Of GnRH Receptor From The Pituitary Of Bonnet Monkey (Macaca Radiata) And Functional Studies With The Antiserum To GnRH Receptor
(Indian Institute of Science, 2005-11-23)GnRH is a decapeptide hormone, which plays a major role in the process of mammalian reproduction. It is synthesized by the hypothalamus and binds to its cognate receptor on the pituitary, to bring about the release of ... -
Studies on Efrapeptins
(2011-11-17) -
Studies On Heat Shock Protein 60 From Plasmodium Falciparum
(2010-09-14)Malaria is caused by a protozoan parasite belonging to the genus Plasmodia. Plasmodium falciparum is responsible for the fatal form of human malaria. Spread of drug resistant parasites warrants for sound biological ... -
Studies on Interactions between ARE Binding Proteins and Splicing Factors and their Role in Altered Splicing of PDGF-B ORF
(2018-03-03)Pre-mRNA splicing is an important level in posttranscriptional gene regulation that is essential for accurate protein synthesis and generating protein diversity. The abundance of cryptic splice sites and long intronic DNA ... -
Studies on Novel Functional Responses of Mouse Peritoneal Macrophages to Interferon-gamma : Roles of Nitric Oxide Synthase 2
(2018-04-18)Interferons are known cytokines that display antiviral, anti-proliferative and immuno-modulatory functions in the host. Interferon-gamma (Ifnγ) is the only type II family interferon that binds to the heterodimeric receptor ... -
Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners
(2010-03-26)PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ... -
Studies On The Functional Roles Of Peptidase N, A M1 Family Member, During Stress And Infection
(2014-08-11)The cytosolic protein degradation pathway, performed by ATP-dependent proteases and ATP-independent peptidases, plays important roles in several cellular activities, e.g. cell division, cell cycle progression, intracellular ... -
Studies On The Mechanism Of Uracil Excision Repair In Escherichia Coli And Structure-Function Relationship Of Single Stranded DNA Binding Proteins From Escherichia Coli And Mycobacterium Tuberculosis
(2014-12-11)To maintain the genomic integrity, cell has evolved various DNA repair pathways. Base Excision Repair pathway (BER) is one such DNA repair pathway which is dedicated to protect DNA from small lesions such as oxidation, ... -
Studies On The Structural And Biological Properties Of Rotavirus Enterotoxigenic Non-structural Protein 4 (NSP4)
(2013-04-01)Rotavirus is the major cause of infantile gastroenteritis. Each year more than 600,000 young children are estimated to die in developing countries throughout the world. Rotavirus infection can be either symptomatic or ... -
Study To Map The Functional Domain Of Glycodelin
(2011-08-22) -
Synthesis and Conformational Analysis of Peptides Containing the Gamma Amino Acid Residue Gabapentin
Insertion of amino acid residues into all polypeptide backbones leads to an expanded repertoire of secondary structures. In the present thesis an attempt has been made to explore the conformational properties of the ... -
Targeting RAD51C Pathological Mutants by Synthetic Lethality and Extended Functions of RAD51C/XRCC3 in Mitochondrial Genome Maintenance
To counteract the potentially calamitous effects of genomic instability in the form of double-strand breaks (DSBs), cells have evolved with two major mechanisms. First, DNA non¬homologous end joining (NHEJ) which requires ... -
Targeting The CD4 Biniding Site In HIV-1 Immunogen Design
(2016-11-15)Over three decades have passed since the discovery of HIV-1, yet an AIDS vaccine remains elusive. The envelope glycoprotein of HIV-1 gp120, is the most exposed protein on the viral surface and thus serves as an important ...