Browsing by Advisor "Ananthasuresh, G K"
Now showing items 1-20 of 22
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A Continuous Optimization Approach To Protein Design With Structural And Functional Constraints
(2013-04-30)We have developed a novel computational approach to functional de novo protein design using gradient based continuous optimization techniques. Motivated by many engineering applications in which a cost function is optimized ... -
Design And Development Of Miniature Compliant Grippers For Bio-Micromanipulation And Characterization
(2017-05-24)Miniature compliant grippers are designed and developed to manipulate biological cells and characterize them. Apart from grippers, other compliant mechanisms are also demonstrated to be effective in manipulation and ... -
Design Of Two-Axis Displacement-Amplifying Compliant Mechanisms Using Topology Optimization
(2010-07-14)This thesis deals with the design of two-axis displacement-amplifying compliant mechanisms (DaCMs) using topology optimization. The two-axis compliant mechanisms considered here are XY positioners and two-axis inertial ... -
Design, Fabrication and Characterization of Low Voltage Capacitive RF MEMS Switches
(2018-08-11)This dissertation presents the design, fabrication, and characterization of low-voltage capacitive RF MEMS switches. Although, RF MEMS switches have shown superior performance as compared to the existing solid-state ... -
Development Of Micromachined And Meso-Scale Multi-Axis Accelerometers With Displacement-Amplifying Compliant Mechanisms
(2017-02-22)Simultaneously achieving high-sensitivity and a large resonance frequency of micromachined accelerometers is difficult because of the inherent trade-off between the two. In this thesis, we present a mechanical displaceme ... -
Discrete particulate description of elastic structures undergoing geometrically nonlinear deformation and dynamic particle interaction
The mechanical behaviour of deformable bodies in a particulate environment has been an area of increasing interest across a wide spectrum of systems and scale. A composite ensemble of deformable structures and discrete ... -
A Feasibility Map-Based Framework and Its Implementation for Selection in Engineering Design
(2018-06-26)A pragmatic method for selecting components and devices from a database or parameterized models is developed in this thesis. The quantitative framework presented here is sufficiently general to accommodate an entire device ... -
Feasible and Intrinsic Kinetoelastostatic Maps for Compliant Mechanisms
(2018-03-06)Despite many advances in the design methods for compliant mechanisms, it is still not possible to know if a set of user-specifications has a solution. Furthermore, practical considerations such as failure limits and ... -
Force-Amplifying Compliant Mechanisms For Micromachined Resonant Accelerometers
(2013-04-04)This thesis work provides an insight into the design of Force-amplifying Compliant Mechanisms (FaCMs) that are integrated with micromachined resonant accelerometers to increase their sensitivity. An FaCM, by mechanically ... -
Frequency-Tuning and Dynamic Simulation of Electrostatically Actuated Beams
(2018-01-03)The resonance frequency of electrostatically actuated micromachined beams can be tuned substantially by applying a DC voltage bias, first by decreasing the frequency until the onset of pull-in and then by increasing it by ... -
Graph Spectral Methods for Analysis of Protein Structures
Network representation of protein structures is an information-rich mode of examining protein structure, dynamics and its interactions with biomolecules. Graph spectral methods are extremely useful and powerful in analysing ... -
A Haptic Simulator for Gastrointestinal Endoscopy : Design Development and Experiments
(2018-09-04)Endoscopy is an involved clinical practice requiring considerable skill in performing the procedure. Virtual reality together with haptics offers immersive, flexible, and cost-effective platform for training in endoscopic ... -
Investigations into the changes in biomechanics of liver cells upon HCV infection
Biomechanics is an important regulator of cell function. Active (external forces) as well as passive (substrate stiffness) mechanical stimuli from the cell microenvironment can alter fundamental aspects of cell function ... -
Non-Dimensional Kinetoelastic Maps for Nonlinear Behavior of Compliant Suspensions
(2018-02-18)Compliant suspensions are often used in micromechanical devices and precision mechanisms as substitutes for kinematic joints. While their small-displacement behavior is easily captured in simple formulae, large-displacement ... -
Pragmatic Design of Compliant Mechanisms using Selection Maps
(2018-04-02)A pragmatic method for designing compliant mechanisms is developed in this thesis, by selecting among existing mechanisms one that may be modified as required. This method complements existing techniques by answering ... -
Static Balancing of Rigid-Body Linkages and Compliant Mechanisms
(2018-03-07)Static balance is the reduction or elimination of the actuating effort in quasi-static motion of a mechanical system by adding non-dissipative force interactions to the system. In recent years, there is increasing recognition ... -
Statics of Shallow Bistable Arches
Bistable arches have two force-free stable equilibrium configurations. They also show multimodality by switching between their stable states in multiple deformation pathways. These two attributes and their nonlinear ... -
Studies for Design of Layered Ceramic Armour Inspired by Seashells
(2018-06-26)Pearly layers in seashells, also known as nacreous layers, are reported to be three orders of magnitude tougher than their primary constituent, aragonite. Their high toughness is attributed to a particular structure of ... -
Synthesis of Conceptual Designs for Sensors
(2017-11-24)A computer-aided technique is developed in this thesis to systematically generate concepts for sensors of a wide variety. A database of building blocks, based on physical laws and effects that capture the transduction rules ... -
Topological Derivative-based Optimization of Fiber-reinforced Structures, Coupled Thermoelastic Structures, and Compliant Mechanisms
The topological derivative of a functional quantifies the sensitivity with respect to an infinitesimal domain perturbations such as a hole, an inclusion, a source term, a crack, etc. In this thesis, topological derivatives ...