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Aβ42-mediated dendritic spine loss in an in-vitro model of Alzheimer’s disease
The results from this study establish the molecular mechanism underlying the Aβ42-mediated dendritic spine loss observed in the APP/PS1 mouse model of AD. Further, this study highlights the role of Aβ42 in altering the ...
Novel Therapeutic Targets for Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by
impaired memory and other cognitive deficits. Even though the genes associated with
familial AD were discovered more than three decades ...