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Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the
primary cellular barrier against the extracellular environment. The high-density of embedded
proteins and glycosylated molecules ...
Paper microfluidic tools to improve the sensitivity and dynamic range of point-of-care immunoassays
Over the past decade, developing affordable home-based tests to diagnose infectious diseases has become a pressing need. The lateral flow immunoassay (LFIA) is the most successfully commercialized point-of-care immunoassay. ...
Inkjet-Printed Ag Nanomaterials based Strain Sensors for Wearable Sensing Applications
Of late, the demand of wearable sensors has exponentially risen. For example, strain sensors that can be worn and are skin mountable play a significant role in the areas of human motion detection, healthcare, soft robotics, ...
Effect of Cobalt Content on Microstructure and Strength in Severely Cold Drawn Ni-Co wires
The future upcoming technologies in aerospace, transport and nuclear industries demand materials with superior mechanical properties that are also economically viable. The quest to achieve theoretical strength of material ...
Multi-linear Disassembly Path Determination: A Geometric Approach
This thesis presents a geometric approach for determining the orientation-preserving disassembly paths of polyhedral
assembly components. Exact disassembly path determination of the components is essential because the ...
Extraction of Equivalent Uniaxial Plastic and Viscoplastic Behavior from Bending Using a Mechanistic Approach
The present work is aimed at the extraction of material’s yield and creep parameters using
cantilevers by conducting constant deflection rate and constant load tests respectively.
Under the assumption of Euler-Bernoulli’s ...
Modelling spatial and non-spatial conflicts across multiple design domains
This thesis aims to detect spatial and non-spatial conflicts in product design arising out of requirements in different design domains. Handling such conflicts requires modelling the non-geometric knowledge outside the ...
Approaches to Regional Analysis of Hydro-Meteorological Processes and Extremes
Regional analysis of hydrometeorological variables (e.g., evapotranspiration, precipitation), hydrological processes (e.g., runoff), and their extremes (e.g., drought, floods) is essential for various applications. The ...
Geoelectrical Characterization for Relating Electrical Resistivity and Geotechnical Properties of Soils
This thesis proposes electrical resistivity measurement as a potential method to characterize different types of geomaterials under different environmental conditions. Electrical resistivity method is a promising non-destructive ...
Probabilistic design and optimization of foundations on cohesionless soil using surrogate models
The design of foundations depends on the properties of soil, which are affected by various forms of uncertainties. These uncertainties affect the foundation performance and hence are considered in the deterministic design ...