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MOLECULAR GENETIC ANALYSIS OF THE TUBEROUS SCLEROSIS COMPLEX
(Indian Institute of Science, 2005-02-21)
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects several organs in the human body including the brain, heart, kidneys, eyes, skin, spleen, liver and lungs [Roach, et al., 1999]. TSC is ...
Study of Ca2+-Mediated Signal Transduction During Embryogenesis In Sandalwood (Santalurm Album L.) And Characterization Of An Early Development-Specific CDPK
(Indian Institute of Science, 2005-12-08)
Calcium ion plays a pivotal role as second messenger during signal/response coupling in plant cells (Trewavas, 1999). Elevations of cytosolic Ca2+ occur in plants as a consequence of abiotic and biotic stresses, environmental ...
Functions Of Nucleosomes And Other Regulatory Factor(S) In Homologous Recombination Promoted By RecA Protein
(Indian Institute of Science, 2005-04-18)
Homologous genetic recombination occurs during the life cycle of virtually every organism Genetic studies especially in prokaryotes and fungi have defined the rules of recombination, led to the characterization of alternate ...
Mycobacterium tuberculosis RecA intein, a novel LAGLIDADG homing endonuclease, displays dual target specificity in the presence of alternative cofactors
(Indian Institute of Science, 2005-05-10)
Mobile inteins and introns are genetic elements capable of self-propagation by “homing” into host genes and occur in entire taxonomy: eubacteria, eukarya, archaea and viruses. The process of “homing” is promoted by an ...
Gene Expression During Cytokinin-Induced Haustoria Formation in Cuscuta Reflexa, Roxb
(Indian Institute of Science, 2005-04-19)
How multicellular organisms develop from a single-celled fertilized egg or zygote that in no way resembles the adult form is one of the major challenges in biology The phase of rapid cell division that follows fertilization ...
Cloning and Expression of a Diagnostic Antigen for Invasive Amoebiasis
(Indian Institute of Science, 2005-04-29)
A crude extract of axenically grown amoebae was used as antigen in order to develop an AB microELISA for the detection and quantitation of E. histolytica-specific IgG antibodies. This ELISA was used to screen individual ...
Nuclear Behaviour In Heterokaryons : Genetic And Molecular Analysis Of (his-3+ his-3+) Heterokaryons Of Neurospora Crassa
(Indian Institute of Science, 2005-12-06)
In contrast to plant and animal cells, the fungal cells are multinucleate. A consequence of their multinucleate condition is heterokaryosis — the occurrence of genetically different nuclei in a common cytoplasm. In nature ...
Cytotoxic T lymphocyte Responses Against Japanese Encephalitis Virus In Mice: Specificity And Immunotherapeutic Value
(Indian Institute of Science, 2005-10-07)
Cytotoxic T Lymphocytes (CTL) are known to play an important role in clearing infectious virus from infected hosts in a variety of viral infections. Depending on the type of virus and mode of virus entry both class I and ...
Identification of Tropomyosin as the Major Cross-Reacting Crustacean Allergen
(Indian Institute of Science, 2005-04-25)
Seafood including crustaceans, on ingestion, are known to provoke gastrointestinal as well as systemic allergic reactions. Crustaceans are aquatic arthropods with a chitinous exoskeleton and include shrimp, lobster, prawn ...
Studies On The Molecular Mechanism Of Cytokinin Action: Involvement Of Ca2+, Protein Kinase And Concurrent Protein Synthesis In Signaling Of Cytokinin-Induced Expression Of Pathogenesis-Related Enzymes In Cucumber
(Indian Institute of Science, 2005-12-08)
Phytohormones act as signals to regulate plant growth and development by modulation of gene expression in response to internal developmental cues or external environmental stimuli, such as light and pathogen infection. ...