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Identification of Therapeutic Targets for Oral Squamous Cell Carcinoma
(2018-04-03)
Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer, with a
worldwide incidence of 275,000 new cases annually (Warnakulasuriya, 2009). Globally, the head and neck carcinoma represents a major cause ...
Transcriptional and Posttranscriptional Regulation of the Tumor Suppressor CDC73 in Oral Squamous Cell Carcinoma : Implications for Cancer Therapeutics
(2018-04-16)
CDC73, also known as HRPT2, is a tumour suppressor gene whose expression is lost or downregulated in parathyroid, renal, breast, uterine and gastric cancers. However, the reports regarding the role of CDC73 in oral squamous ...
Proteomic Approaches to Study Glioma Development, Progression and Therapy
(2018-04-02)
Astrocytoma, the tumor of astrocytic origin, accounts for about 60 % of the primary
brain tumors. As per World Health Organization grading system, astrocytoma is classified as circumscribed astrocytoma (Grade I; pilocytic ...
Role of DNA Methylation in Glioblastoma Development
(2018-04-11)
Glioblastoma (GBM) is the most common and malignant of the glial tumors. These tumors may develop from lower-grade astrocytomas (diffuse astrocytoma; grade II or anaplastic astrocytoma; grade III) through a progressive ...