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Activation Of Glycoprotein Hormone Receptors : Role Of Different Receptor Domains In Hormone Binding And Signaling
(2014-07-16)
The glycoprotein hormones, Luteinizing Hormone (LH), human Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) are heterodimeric proteins with an identical α-subunit ...
Cyclic AMP In Mycobacteria Adenylyl Cyclases And Cyclic AMP Receptor Proteins
(2013-01-28)
The discovery of cyclic AMP (cAMP), nearly 50 years ago by Sutherland radically altered the appreciation of metabolic regulation. Since then the presence of cAMP and its tremendous physiological impact has been demonstrated ...
Identification Of Domains Of The Follicle Stimulating Hormone Receptor Involved In Hormone Binding And Signal Transduction
(2010-10-08)
The glycoprotein hormones, Luteinizing Hormone (LH), human Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) are heterodimeric proteins with an identical α-subunit ...
Characterization Of Down Regulated Genes In Astrocytoma
(2011-07-27)
Gliomas are the most common primary brain tumors and include astrocytomas, oligodendrogliomas and oligoastrocytomas. Astrocytomas have a high frequency of occurrence as compared to the other gliomas and several studies ...
Estradiol Induced Changes In Neuronal Excitability And Neuron-Astrocyte Signaling In Mixed Hippocampal Cultures
(2010-03-02)
One of the defining characteristics of the brain is its plasticity, which is the ability to alter and reorganize neuronal circuits. The brain is constantly being shaped and moulded by the external world through endogenous ...
Studies On The Roles Of Intracellular Ca2+ And Reactive Oxygen Species During CD4+ T Cell Activation : Influence Of Signal Strength
(2011-03-08)
Optimal CD4+ T cell activation is key to the generation of a productive immune response. Naïve circulating CD4+ T cells are quiescent under normal conditions and undergo activation only upon encounter of the T cell receptor ...
Effect Of Glycodelin A On Cells Of The Immune System Insights Into GdA-Induced Signaling In Monocytes, B And NK Cells
(2010-04-06)
Glycodelin is a 162 amino acid dimeric, glycosylated, secretory protein of the lipocalin superfamily. Its classification as a lipocalin(carriers of small hydrophobic molecules) is based mainly on the presence of lipocalin ...
Delineation Of Signaling Events Regulating Mycobacterium Bovis BCG Induced Expression Of MMR-9 And SPI6 : Possible Implications For Immune Subversion Mechanisms
(2013-08-30)
One key to the pathogenic potential of the mycobacteria lies in their capacity to resist destruction by infected macrophages and dendritic cells. Robust host immune responses during mycobacterial infection often involve a ...