Mycobacterium tuberculosis, the causative agent of tuberculosis, has become a global health concern. This calls for a dire need to understand various aspects of mycobacterial physiology in order to design better strategies ...

Male reproductive success in systems exhibiting sexually selected traits can be driven by male mating effort in sexual signals and in the production of nuptial gifts. Male mating effort can be determined by various biotic ...

Ribosome inactivating proteins (RIPs) from plants, fungi or bacteria are extremely lethal due to their N-glycosidase activity on eukaryotic ribosomal RNA. As the name indicates, these toxins inactivate ribosomes; thereby ...

All living systems are composed of plethora of biomolecules. There are various types of biomolecules such as proteins, DNA, RNA, carbohydrates and metabolites. All the reactions in a biological system involve interactions ...

Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant chemotherapy with temozolomide. ...

Remote retrieval of declarative memories has been under investigation for a long time. After acquisition, long-term encoding of memories happens through crosstalk across multiple brain regions. Through systems consolidation, ...

Chromatin is a dynamic structure which reorganizes to support numerous chromosomal processes. Various histone and non-histone proteins are involved in chromatin organization. One such group of non-histone proteins, known ...

Salmonellosis is a major health concern which causes significant morbidity and mortality worldwide. Infection with Salmonella Typhimurium leads to self-limiting diarrhea in healthy individuals and invasive disease in ...

Helicobacter pylori is a gram-negative epsilon proteobacterium infecting half of the world population. H. pylori is a naturally competent bacterium with a huge repertoire of Restriction-Modification (RM) systems. The ...

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system (CNS). The synaptic levels of GABA are controlled by the activity of GABA transporters (GATs) present in the presynaptic ...