The process of protein synthesis is a fundamental and key event in living organisms. The process of translation initiation is assisted by specific proteins known as initiation factors. In bacteria, three initiation ...

The global pandemic caused by SARS-CoV-2 has resulted in millions of deaths worldwide, highlighting the urgent need for effective vaccines. The trimeric spike glycoprotein, particularly the receptor-binding domain (RBD), ...

RNA homeostasis is maintained by synchronizing RNA synthesis and RNA degradation. These processes are synchronized to growth conditions and environmental stimuli, thus enabling bacterial survival in diverse environmental ...

Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channel stands out for its unique characteristics, including sensitivity to transmembrane voltage and cyclic nucleotides, as well as its non-selective passage ...

The complex dynamics and responses of biological systems to environmental cues are shaped by their inherent plasticity and adaptability. This biological plasticity, operational at multiple levels - ranging from the molecular ...

Familiarity with something implies having a close acquaintance with that item, generally acquired over a period of time. Apart from single items, we have experienced getting familiar with a pair of items (like a mouse and ...

Heterogenous ribonucleoproteins (hnRNPs) are a class of proteins initially discovered to protect the nascent transcripts before they develop into primary mRNAs. They are involved in almost all the stages of mRNA metabolism, ...

This thesis investigates two main aspects of neuronal integrity and gut health. Firstly, it examines the intricate relationship between neuronal integrity and the maintenance of gut homeostasis in Drosophila melanogaster. ...

In eutherian female mammals, one of the X-chromosomes gets inactivated to compensate for the expression dosage of X-linked genes between the sexes. X-chromosome inactivation (XCI) serves as a paradigm of epigenetic memory ...

The peripheral membrane protein repertoire is around 25% composed of the Pleckstrin homology domain (PHD). PHD are component of the multidomain protein and plays the role of an adaptor in recruitment of these proteins ...