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Functions Of Nucleosomes And Other Regulatory Factor(S) In Homologous Recombination Promoted By RecA Protein
(Indian Institute of Science, 2005-04-18)
Homologous genetic recombination occurs during the life cycle of virtually every organism Genetic studies especially in prokaryotes and fungi have defined the rules of recombination, led to the characterization of alternate ...
Identification And Characterisation Of Two Silencing Barrier Sequences In Saccharomyces Cerevisiae
(2010-07-21)
In eukaryotic cells, genomic DNA exists as chromatin in association with histone octamers called nucleosomes, and various other chromatin proteins. Chromatin structure varies along the chromosome and this influences the ...
Topoisomerases from Mycobacteria : Insights into the Mechanism, Regulation and Global Modulatory Functions
(2018-03-09)
The eubacterial genome is maintained in a negatively supercoiled state which facilitates its compaction and storage in a small cellular space. Genome supercoiling can potentially influence various DNA transaction processes ...
DNA Repair Proteins in Mycobacteria and their Physiological Importance
(2018-03-09)
DNA repair proteins in mycobacteria and their physiological importance
Mycobacterium tuberculosis, the causative organism of tuberculosis, resides in the host macrophages where it is subjected to a plethora of stresses ...
Epigenetic Modulators of Glioma : From miRNAs to Chromatin Modifiers
(2018-02-20)
The glial cells of the brain and the peripheral nervous system retain the capacity to divide and proliferate throughout the lifespan of an individual and thereby have the propensity to give rise to the most adult neurological ...
Modulation Of Bacterial Pathogenesis By Curcumin
(2014-07-03)
Foodborne diseases are one among the diseases with high morbidity and mortality rate. The concern is raised with the emergence of pathogenic strains that are resistant to the available set of antibiotics. Conventional ...
Functional Characterization Of The Saccharomyces Cerevisiae Splicing Factor, Prp17 In pre-mRNA Splicing And Cell Cycle Progression: An Analysis Through Global Expression Profiling, Protein Interactions And Spliceosomal Associations
(2007-08-30)
The presence of introns in all the eukaryotic genomes identified so far underscores the fundamental and ubiquitous role of pre-mRNA splicing. The spliceosomal machinery, comprised of five small nuclear RNAs and several ...
Role Of Matrix Protein Of Rinderpest Virus In Viral Morphogenesis
(2008-10-20)
Rinderpest virus is an enveloped Nonsegmented Negative Stranded RNA Virus (NNSV) belonging to the genus Morbillivirus in the Family Paramyxoviridae and the causative organism for “cattle plague”. The virion has a transport ...