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Processing Of DNA Recombination And Replication Intermediates By Mycobacterium Tuberculosis RuvA And RuvB Proteins
(2013-06-14)
Homologous recombination (HR) is a highly conserved cellular process involved in the
maintenance of chromosomal integrity and generation of genetic diversity. Biochemical and genetic studies have suggested that HR is ...
Helicobacter Pylori Restriction-Modification Systems : Possible Roles Beyond Genome Protection
(2013-06-06)
Helicobacter pylori is one of the most potential and successful human pathogen which colonizes atleast 50% of world population. One of the important characteristics of this pathogen is the degree of allelic diversity and ...
The Mechanism Of Fragility Of The BCL2 And HOX11 Breakpoint Regions During t(14;18) And t(10;14) Chromosomal Translocations In Lymphoid Cancers
(2014-08-05)
Haematological cancers like leukemia and lymphoma are characterized by genetic abnormalities, specifically chromosomal translocations. Analyses of the translocation breakpoint regions in patients have shown that some loci ...
Insights Into Transcription-Repair Coupling Factor From Mycobacterium Tuberculosis
(2014-12-01)
Introduction
Nucleotide excision repair (NER) is a highly conserved pathway involved in repair of a wide variety of structurally unrelated DNA lesions. One of the well characterized NER systems is from E. coli which ...
Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells
(2013-07-18)
Recombination Activating Genes (RAGs) orchestrate the process called V (D) J recombination, which enables the vertebrate adaptive immune system to specifically recognize millions of antigens. During this recombination ...
Functions For OsMADS2 And OsMADS1 As Master Regulators Of Gene Expression During Rice Floret Meristem Specification And Organ Development
(2013-06-06)
Plant reproductive development begins when vegetative shoot apical meristems change their fate to inflorescence meristems which develop floral meristems on the flanks. This process of meristem fate change and organ development ...
Metabolism Of Queuosine, A Modified Nucleoside, In Escherichia Coli And Caenorhabditis Elegans And Dual Function Of Bovine Mitochondrial Initiation Factor 2 As Initiation Factors 1 And 2 In Escherichia Coli
(2009-06-29)
The studies reported in this thesis address firstly, the biology of a modified nucleoside, Queuosine (Q) and secondly, the properties of mitochondrial translation initiation factor 2. A summary of the relevant literature ...