Browsing Division of Biological Sciences by Title
Now showing items 694-713 of 1740
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Isolation and Charecterization of polysaccharide degrading enzymes of chaetomium thermophile var. coprophile
ISOLATION AND CHARACTERIZATION OF POLYSACCHARIDE DEGRADING ENZYMES OF Chaetomium thermophile var. coprophile” SUBMITTED BY: RAMESH KUMAR GANJU FOR THE Ph.D. DEGREE OF INDIAN INSTITUTE OF SCIENCE, BANGALORE – 560012 The ... -
Isolation and functional charecteristics of xylanases and cellulases of thermoascus aurantiacus
ISOLATION AND FUNCTIONAL CHARACTERISTICS OF XYLANASES AND CELLULASES OF THERMOASCUS AURANTIACUS” SUBMITTED BY KIRAN KHANDKE FOR THE Ph.D. DEGREE OF THE INDIAN INSTITUTE OF SCIENCE, BANGALORE - 560 012 The thesis deals with ... -
Isolation And Identification of Tropane Alkaloid Producing Endophytic Fungi from Datura Metel L., And Studies on Colletotrichum Boninense Recombinant Putrescine N-mehtyltransferase
(2017-10-11)Datura metel is a herbaceous plant found in almost all tropical parts of the world. It belongs to the family Solanaceae whose members, viz. Duboisia, Atropa, Hyoscyamus and Datura plants are known to produce tropane ... -
Isolation and studies of the structure and interactions at the active site of sheep liver serine hydroxymethyltransferase
Serine hydroxymethyltransferase can be considered as the first enzyme in the pathway for the interconversion of folate coenzymes (Fig. 1) and is the source of C1 fragments for the biosynthesis of a large number of biologically ... -
Isolation of a ribonucleus from grain sorghum (Sorghum vulgare pers) and initial studies on its physico-chemical properties and mode of action
The present thesis is concerned with the detection, isolation and characterization of a ribonuclease from a cereal, namely grain sorghum (Sorghum vulgare Pers.). Grain sorghum is a very important cereal forming the staple ... -
Isolation, kinetic mechanism and active site studies on sheep liver 5, 10-methylenetetrahydrofolate reductase
(i) A major landmark in the history of science is the discovery of the biochemical and physiological functions of vitamins. Folic acid, which was isolated from spinach leaves for the first time, was shown to be an anti ... -
Isolation, Structure Elucidation and Functional Characterization of a Novel Cytotoxic Secondary Metabolite Phomafuranone, 2-Hydroxy-2, 4-dimethyl-5-[-1-propen-1-yl]-3(2H)-furanone, from Phoma tropica an Endophytic Fungus Isolated from Mappia foetida.
Cancer has become the leading disease-related cause of death in the human population. For example, in the United States, cancer is the second leading cause of death behind cardiovascular disease, and it is projected that ... -
Isolation, structure elucidation and increasing anticancer efficacy of an anti-cancer secondary metabolite from a marine-derived endophytic fungus, Aspergillus species
Cancer is the leading cause of mortality globally, contributing to ~10 million fatalities in 2020, or roughly one in every six deaths, according to global cancer statistics 2020. Around 50% of all small molecules approved ... -
Japanese Encephalitis Virus Infection In Vitro : Role Of Type-I Interferons And NF-kB In The Induction Of Classical And Nonclassical MHC-I Molecules
(2011-03-08)Japanese encephalitis virus (JEV) is one of the major causes of encephalitis in Asia. JEV causes serious inflammation of the brain, which may lead to permanent brain damage and has a high mortality rate. Almost 3 billion ... -
JEV Infection in the Brain and its effects on the Immune Response
Using mouse as a model system, the effects of viral infection in the brain on: (A) Peripheral lymphoid organ - spleen (B) Central lymphoid organ - thymus were studied. Key Findings Mice infected with 400 pfu of JEV through ... -
Kinetic and regulatory properties of a monomeric flavokinase from mung bean (Vigna radiata) Seeds
The harmonious coordination among the myriad of reactions operating simultaneously in a cell is achieved by conformational response of key enzymes to ligand binding. Most often, in a highly branched, interlinked metabolic ... -
Kinetic and thermodynamic study of a non-inactivating K+ current in a gonadotroph cell-line
aT3-1 is a gonadotroph cell line derived from mice by oncogenic transformation of the pituitary, using simian virus, and secretes a subunit of follicle-stimulating hormone in response to hypothalamic peptide gonadotropin-releasing ... -
Kinetic studies on enoyl- ACP reductase from plasmodium falciparum : A potential target of antimalarials
Enoyl-ACP reductase (FabI) catalyzes the rate-determining step in the type II fatty acid synthesis (FAS) pathway. This pathway is present in plants and bacteria. However, the recent demonstration of this pathway in the ... -
Kinetic, Catalytic and Epigenetic Properties of HpyAXVII DNA Methyltransferase – a Phasevarion in the Human Pathogen Helicobacter pylori
Helicobacter pylori is the leading cause of gastric cancer in human beings. It is a helix-shaped, Gram-negative, motile bacteria that colonizes the gastric mucosa and eventually the gastric epithelium. It has an overabundance ... -
Large Herbivore Dung Decomposition: Effects on Nutrient Cycling in a Tropical Forest of Southern India
Large herbivores can selectively feed on nutrient rich resources, resulting in regular deposition of high quality organic matter in the form of dung. In tropical forests such as in southern India it is estimated that large ... -
Large-Scale Structural Analysis of Protein-ligand Interactions : Exploring New Paradigms in Anti-Tubercular Drug Discovery
(2018-08-13)BIOLOGICAL processes are governed through specific interactions of macromolecules. The three-dimensional structural information of the macromolecules is necessary to understand the basis of molecular recognition. A large ... -
Lectin from mimosa invisa L and its role in rhizobium recognition
Understanding the specificity of the legume-Rhizobium symbiosis may help in improving biological nitrogen fixation in several ways. The causes for this specificity have been studied in only a few systems like clover, ... -
Legume lectin carbohydrate regognition : clonning of peanut( arachits hypogea) and winged bean (psophocarpus tetragono;obus) agglutinins and reswsign of carbohydrate specificity of PNA
Recognition of cell-surface carbohydrates by lectins has wide implications in important biological processes such as protein targeting to cellular compartments, homing of lymphocytes, host-pathogen interactions, and ... -
A Ligase IV/XRCC4-dependent single strand break repair pathway for the maintenance of A/T-rich regions during DNA replication in mammals
The DNA in our cells is under constant threat from various exogenous and endogenous sources. To ensure error free and faithful transmission of hereditary material, human cells employ several DNA repair pathways. Mammalian ... -
Light-And Cytokinin-Regulated Plastid And Nuclear Gene Expression In Cucumber (Cucumis Sativus L)
(Indian Institute of Science, 2005-12-06)Light and phytohormones, such as cytokinins, have been known to play a pivotal role in numerous physiological processes in plant cells. Previous work in our laboratory has revealed the light- and cytokinin- modulated changes ...