etd AT Indian Institute of Science: Recent submissions
Now showing items 841-860 of 6569
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Model-based Safe Deep Reinforcement Learning and Empirical Analysis of Safety via Attribution
During initial iterations of training in most Reinforcement Learning (RL) algorithms, agents perform a significant number of random exploratory steps, which in the real-world limit the practicality of these algorithms ... -
Lab to Point-of-Need Technology: Solving the A3 puzzle of in-vitro diagnostics
The role of medical diagnostics is morphing rapidly in the face of imminent challenges such as pandemic preparedness. Correspondingly, in-vitro diagnostics are evolving — growing beyond the traditional Centralized Diagnostic ... -
Understanding Nonhomologous DNA End Joining: Novel Insights Into Mechanism and Regulation
This study has provided new insights into the mechanistic details of NHEJ and showed that DNA sequence around the break site can be a factor in determining which proteins involved in NHEJ might be recruited with a higher ... -
Mechanistic insights into the role of miR‐6741‐3p in oral squamous cell carcinoma pathogenesis
Many functional studies and clinical analysis have linked miRNA dysregulation as a causative factor for tumor initiation and progression. Overexpression of oncogenic miRNAs and downregulation of tumor suppressor miRNAs are ... -
Geoelectrical Characterization for Relating Electrical Resistivity and Geotechnical Properties of Soils
This thesis proposes electrical resistivity measurement as a potential method to characterize different types of geomaterials under different environmental conditions. Electrical resistivity method is a promising non-destructive ... -
Minerals to Functional Materials: Comprehensive Evaluation of Vanthoffites and Related Materials towards Futuristic Multifunctional Applications
The thesis provides a systematic investigation of materials derived from different mineral species such as vanthoffite and related minerals structures. Search of new multifunctional materials continues to be a challenge ... -
On symmetries of and equivalence tests for two polynomial families and a circuit class
Two polynomials f, g ∈ F[x1, . . . , xn] over a field F are said to be equivalent if there exists an n×n invertible matrix A over F such that g = f(Ax), where x = (x1 · · · xn)T . The equivalence test (in short, ET) for ... -
Hydrodynamic and hydromagnetic instabilities leading to turbulence in astrophysical accretion disks and their connection to laboratory shear flows
Accretion disks are astrophysical objects formed around a denser object, mainly in the form of a disk. In an accretion disk, matter spirals in and falls onto the central object. To match the observations, the underlying ... -
Supramolecular Self-assembly of Diketopyrrolopyrrole with Emergent Photophysics and Unprecedented Photoconductivity
Structural fluctuation in organic molecular semiconductors often plays a key role in fragmenting the conducting pathways even in their condensed phases due to the large fraction of free volumes, acting as trap sites for ... -
Improving Healing Outcomes in Diabetic Wounds by Understanding and Modulating Immune Responses
Diabetic Foot Ulcers (DFUs) are chronic wounds that show delayed or absence of healing in individuals with diabetes. Currently, diabetic wounds are managed clinically through regular debridement, pressure off-loading, ... -
Polymerizable Porogen – Direct generation of internally functionalized porous polymers
Bicontinuous functional porous polymers are desirable in terms of pore accessibility, particularly for applications in templating, chromatographic separation, and catalysis. Bicontinuous morphologies can be obtained by ... -
Experimental Investigation of Electrons In and Above Liquid Helium
Electrons on the surface of liquid helium form a nearly ideal 2-dimensional electron system (2DES). An electron density up to 2 × 10^9 cm-2, known as the critical electron density, can be achieved on the liquid helium ... -
Explorations in the Space of S-Matrices
S-matrix is one of the fundamental observables of the quantum theory of relativistic particles. The quantum dynamics of relativistic particles can be abstractly understood in terms of S-matrix bypassing a Lagrangian ... -
Neural Approaches for Natural Language Query Answering over Source Code
During software development, developers need to ensure that the developed code is bug-free and the best coding practices are followed during the code development process. To guarantee this, the developers require answers ... -
Automated methods of natural resource mapping with Remote Sensing Big data in Hadoop MapReduce framework
For several decades, remote sensing (RS) tools have provided platforms for the large-scale exploration of natural resources across the planetary bodies of our solar system. In the context of Indian remote sensing, mineral ... -
Itaconate Based Novel Amphiphilic Polymer Architectures
Amphiphiles are natural or synthetic molecules consisting of hydrophilic polar head group and hydrophobic non-polar hydrocarbon tail. Beyond a certain concentration, known as critical micellar concentration (CMC), amphiphilic ... -
Electronic Photonic Circuit Design for RF Transceiver
RF over fibre (RoF) based communication system combines features of mm-wave and optical fibre communication. The RoF-based system has the advantage of both optical fibre systems (such as high bandwidth, signal transparency, ... -
Mutational sensitivity of CcdB mutants in their native operonic context
Determining the precise effects of thousands of point mutants on protein structure, stability, and activity is a challenging task. Chapter 1 introduces how next-generation sequencing technologies exploit phenotypic screens ... -
Unravelling the functional role of Arf-like GTPases 14 and 15 in mammalian cells
Small G-proteins of Arf-like (Arl) GTPase subfamily are shown to regulate several cellular processes including intracellular trafficking, cytoskeletal organization, organelle biogenesis, cell adhesion and migration. Around ... -
An electromagnetically actuated mesoscale ball and socket joint for applications in 3-D metrology and electrical characterization
Micro-robotics is concerned with development of robotic systems to manipulate micro-meter sized objects. To develop functional micro-robotic manipulators, it is necessary to develop joints that possess large motion range ...