etd AT Indian Institute of Science: Recent submissions
Now showing items 2561-2580 of 6965
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A Theoretical Study of Thermoelectric Effect for Cross-plane Transport Across Twisted Bilayer Graphene
The thermoelectric effect and the linear response theory is one of the most studied areas in condensed matter physics. In the last few years, the study of Van Der Waals heterostructure has become one of the most promising ... -
Role of SIRT6 in the regulation of mTOR signalling and global protein synthesis
Cells are constantly engaged in the process of making and breaking proteins in a highly organized manner. However, protein synthesis is an energetically expensive process and often competes with other cellular repair and ... -
ROLE OF SIRT6 AND PARP-1 IN MUSCLE HOMEOSTASIS
Sirtuins and PARPs are stress responsive family of proteins regulating genome instability, inflammation, aging-related diseases and energy metabolism. Both sirtuins and PARPs are NAD+ enzymes with deacetylase and ADP-ribose ... -
Malat1 and COP1 mediated host responses orchestrate mycobacterial pathogenesis
Tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), is viewed to be the predominant cause of death arising due to bacterial infection. Further, the emergence of MDR/XDR strains and co-infections has compounded ... -
Studies on the regulatory roles for Retinoic Acid (RA) during host-microbial interaction : implications for S. aureus and C. albicans infections
Chronic inflammatory disorder is one of the leading causes of death worldwide. Association between pathogenic infection and inflammation governs tissue homeostasis, which relies on extensive crosstalk among signaling ... -
Transmit Antenna Selection in Underlay Spectrum Sharing: Role of Power Adaptation, Interference Constraint, and Channel State Information
Spectrum sharing is essential to support high wireless data rates and a large number of wireless connections by the future technologies in the limited spectrum that is available. In underlay spectrum sharing a secondary ... -
Gust Rejection in Insect Flight
Large commercial and military aircraft can fly in turbulent wind conditions except in extreme weather events like cyclones. Smaller man-made vehicles like Micro aerial vehicles (MAVs) and Nano aerial vehicles (NAVs) are ... -
Rapid light sheet fluorescence microscopy for dynamic imaging of living organisms
The primary goal of this thesis is to develop a light sheet based microscopy system that provides non-invasive images having high spatial and temporal resolution. The fluorescence microscopy has become an indispensable ... -
Exploring water dynamics and gas separations in graphene oxide surfaces and nanopores
Graphene oxide (GO) is a chemically functionalized graphene with various oxygen-containing functional groups, such as epoxy (-O-), hydroxyl (-OH), and carboxyl (-COOH) on the basal plane. As a consequence, GOs have hydrophilic ... -
Investigating the Role of Domain Swapping in Aggregation of Globular Proteins
The broad objective of this thesis involves computationally modeling protein aggregation with special emphasis on the role of cosolvents and misfolded states. Chapter 1 contrasts the effect of biologically relevant co-solvents ... -
Microstructure and Shape Memory Behavior of quaternary Ni(50-x)-(Pt/Pd)x-Ti(50-y)-(Hf/Zr)y alloys
Shape memory alloys (SMA) are those class of alloys that can cause shape memory, pseudoelastcity and two-way memory effects due to reversible austenite to martensite phase transformations. The NiTi shape memory alloys ... -
Insights into Network Coding Using Tools From Linear Algebra and Matroid Theory
Traditionally, the transmission of information through a network was carried out using store-and-forward techniques. This entails managing information bits in a network analogous to commodity flow, without mixing or combining ... -
Turbulent Mixing of Multiple-Passive-Scalars
We have studied the mixing of multiple forced passive scalars in 3D homogeneous and isotropic turbulence. The trends of the structure functions for a single scalar, although not very well resolved, seem to be similar to ... -
Development and application of multi-photon microscopy in neuroscience and nanoscience
Neuroscience is at crossroads. Several interdisciplinary optical developments centred around nonlinear optical processes helps in better understanding of brain function at sub-micron and millisecond precision. Traditional ... -
Properties and Applications of Metal Cholate Hydrogels
This thesis presents a detailed study on the unusual properties of silver cholate, applications of lanthanide cholate gels, enhanced luminescence of lanthanides by water, and the mechanism of formation of these gels. ... -
Fast Solvers and Preconditioning Methods in Computational Electromagnetics
Method of Moments (MoM) is an integral equation based solver and is one of the most popular computational techniques to solve complex 3D Electromagnetic problems efficiently and accurately. Compared to the conventional ... -
Role of Mycobacterium tuberculosis DinG and UvrD helicases in unwinding G-quadruplex DNA
Recent studies have demonstrated the role of E. coli UvrD as a replicative helicase that facilitates replication of rolling circle plasmids. Along with dinG and rep helicase, UvrD a so-called “accessory helicase” removes ... -
Understanding intramolecular signal transduction in regulated proteases of the High Temperature Requirement A family
Protein homeostasis in all organisms is a complex process involving regulatory mechanisms that govern protein synthesis, post-translational events and degradation. The protein degradation mechanism serves multiple functions ... -
Electrical transport and noise in polycrystalline 2D van der Waals materials and their grain boundaries
The successful exfoliation of graphene in 2004 ushered in the era of 2D van der Waals materials, paving the way for a wide variety of applications in the field of electronics, optoelectronics, sensors, catalysis, flexible ... -
Design and Analysis of Integrated Optic Waveguide Grating for Sensor and Communication Applications
Waveguide gratings are widely being used for multitude of applications owing to high sensitivity, immunity to electromagnetic interference, multiplexing capabilities, light weight and compactness. Waveguide gratings on ...