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X-Ray Crystallographic Studies Of Designed Peptides And Protected Omega Amino Acids : Structure, Conformation, Aggregation And Aromatic Interactions
(2009-05-18)
Peptides have assumed considerable importance in pharmaceutical industry and vaccine research. Understanding the structural features of these peptide molecules can be effective not only in mimicking natural proteins but ...
Contributions To Venominformatics : Sequence-Structure-Function Studies Of Toxins From Marine Cone Snails. Application Of Order-Statistics Filters For Detecting Membrane-Spanning Helices
(2009-07-21)
Venomous animals have evolved a vast array of peptide toxins for prey capture and defense. Nature has evolved the venoms into a huge library of active molecules with high selectivity and affinity, which could be explored ...
Crystal Structure Of Abrus Precatorius Agglutinin-I (APA-I) : Insights Into The Reduced Toxicity Of APA-I In Relation To Abrin. Formation Of Ordered Nanotubes Through Self Assembly In The Crystal Structures Of Dipeptides Containing α. β-dehydrophenylalanine
(2009-07-22)
Ribosome Inactivating Proteins (RIPs) are protein or glycoprotein toxins that bring about the arrest of protein synthesis by directly interacting with and inactivating the ribosomes. Such toxins are in general, of plant ...
Thermal Fluctuation Spectroscopy And Its Application In The Study Of Biomolecules
(2009-03-03)
The aim of this thesis is to study the energy fluctuations (leading to thermal fluctuations) during thermal and enzymatic denaturation of biological molecules and to study the variation in fluctuations between simple ...
X-Ray Crystallograhic Studies On 2',5', Cyclic And Modified Nucleotides
(2007-09-05)
This thesis presents the crystal structures of 2', 5', cyclic and modified nucleosides / nucleotides. Chapter I gives a brief account of the structural studies on 2', 5' and modified nucleotides. It also presents a short, ...