Browsing by Subject "SARS-CoV-2"
Now showing items 1-6 of 6
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Deciphering the role of host protein HuR in RNA virus life cycle and pathogenesis: Hepatitis C Virus and SARS-CoV-2 as exemplars.
Viruses pose a major threat to human health and the ongoing SARS-CoV-2 pandemic proves as the best evidence for that. Historically, RNA viruses have a major potential to cause such pandemics. They utilise RNA binding ... -
Deep Mutational Scanning Analyses of Protein Stability and Function
Full text Embargo up to Sep 2026 Protein stability is critical to understanding protein function, folding, and interactions within living organisms. It plays a key role in protein engineering, where designing stable ... -
Design and characterization of stabilized mutants of the SARS-CoV-2 Receptor Binding Domain
The global pandemic caused by SARS-CoV-2 has resulted in millions of deaths worldwide, highlighting the urgent need for effective vaccines. The trimeric spike glycoprotein, particularly the receptor-binding domain (RBD), ... -
Immunogen design to enhance Influenza and SARS-CoV-2 vaccine efficacy
Influenza and SARS-CoV-2 are pleomorphic viruses that cause respiratory diseases in humans and present significant public health threats. Vaccination has been essential in controlling the spread of these infections and ... -
Mathematical and Statistical Modeling of Epidemiology of Asymptomatic COVID-19 Infections and Vaccine Design Strategies
A defining feature of the COVID-19 pandemic has been the high prevalence of asymptomatic SARS-CoV-2 infections – laboratory-confirmed cases where individuals never develop symptoms. Accurately estimating the proportion ... -
Molecular Interactions Between SARS-CoV-2 Viral and Human Cellular Factors: Implications for Viral Infection, Replication, and Disease
The COVID-19 pandemic was this century's most significant global public health crisis. The causative agent was SARS-CoV-2, an enveloped, single-stranded positive-sense virus. As an obligate intracellular pathogen, SARS-CoV-2 ...