Browsing by Subject "Bacteria"
Now showing items 1-20 of 24
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An Approach Towards Inactivation of Susceptible and Antibiotic Resistant Bacterial Contamination using Novel Photo–(electro)-catalysts
Water in most rivers in India does not meet the standards for drinking and even for bathing purposes due to the high concentration of coliforms, organic and inorganic contaminants. Overuse, uncontrolled release and careless ... -
Bacterial cellular heterogeneity in inducible gene expression and drug susceptibility
Biological processes are inherently noisy, and such stochasticity can result in significant cell to cell variability in isogenic bacterial populations. Functionally, cellular heterogeneity can have significant impact on ... -
Bipartite pore-forming toxin YaxAB: understanding pore formation using live-cell imaging
Bacteria employ a variety of strategies to invade and colonise the host tissue, including the secretion of toxins to overcome the cellular barrier. Bacterial pore-forming toxins (PFTs) disrupt the lipid bilayer by forming ... -
Characterization of a Staphylococcus aureus multi-enzyme complex involved in the phenotypic switch and host-pathogen interactions
RNA homeostasis is maintained by synchronizing RNA synthesis and RNA degradation. These processes are synchronized to growth conditions and environmental stimuli, thus enabling bacterial survival in diverse environmental ... -
Deciphering the mechanism behind the division of the Salmonella containing vacuole (SCV) and the immunomodulation strategy employed by Salmonella Typhimurium
The genus Salmonella represents flagellated, Gram-negative, rod-shaped anaerobic bacteria which is a leading cause of food-borne illness and causes enteric disease in a wide range of animals. In humans and several warm-blooded ... -
Deciphering the role of outer membrane porins in the pathogenesis of Salmonella enterica serovar Typhimurium
Porins are highly conserved barrel-shaped proteins bound to the bacterial outer membrane and involved in the selective transport of charged molecules across the membrane. They consist of parallel and anti-parallel β sheets ... -
Deep Mutational Scanning Analyses of Protein Stability and Function
Full text Embargo up to Sep 2026 Protein stability is critical to understanding protein function, folding, and interactions within living organisms. It plays a key role in protein engineering, where designing stable ... -
Elucidation of fluid dynamics of bacterial movements and transport processes in natural body fluids and its relation to pathogenesis
The transmission mechanism of respiratory diseases includes routes such as direct or indirect contact, large droplets, and airborne transmission, apart from close contact transmission, which is complex. However, the ... -
Host-Pathogen Interaction Between Staphylococcus Aureus And Murine Macrophages
(2013-09-04)Chapter 1: Introductionn Staphylococci are gram positive rotund bacteria that grow in clusters; and hence get their name. The genus of Staphylococcus comprises of over 30 species of which S. epidermidis and S.aureus are ... -
Identification, characterization, structure, and assembly of type III toxin-antitoxin systems from Escherichia coli
Bacteria adopt several defense strategies to enable their survival against the environmental threats they encounter from time to time. Toxin-antitoxin (TA) systems are being understood as a key bacterial defense mechanism ... -
Immune cell surveillance and death on silicone catheter surfaces drives bacterial biofilm formation
Silicone venous catheters are among the most used medical devices in the world with a prevalence of up to 80% in hospitalised patients. While they are used for several life-saving applications, they are also prone to ... -
Insights on the Evaporation and Precipitation of Pathogen-Laden Respiratory Droplets on Inanimate Surfaces
Disease transmission via fluid ejections from infected individuals is a critical public health concern, particularly in high-risk environments like hospitals, public transport, restaurants, and schools. Respiratory droplets ... -
INTERPIN: identifying INtrinsic transcription TERminators, hairPINs in bacteria
The conversion of DNA to RNA through transcription is an important step in the life cycle of every organism. It ensures that the genetic information in DNA is converted through RNA into instructions/blueprints for the ... -
Investigations on the regulatory role of BglG on the expression of ridA and the pleiotropic effects of bglG deletion in E. coli
The bgl operon of E. coli encodes for the proteins involved in the uptake and catabolism of plant-derived aromatic beta-glucosides, normally associated with the soil environment. The silent state of the operon seen ... -
Pathogen-derived volatiles modulate flight or fight response in Caenorhabditis elegans
In nature, the interaction between two organisms largely relies on their ability to sense and respond to each other, which involves many specific chemicals and signaling pathways. Animals have evolved mechanisms to detect ... -
Photocatalytic and Photoelectrocatalytic systems for water remediation and energy applications
This PhD work consists of two main parts. The first part focuses on photocatalytic systems for water remediation from bacteria and phenolic compounds, and the second part deals with photoelectrocatalytic systems for biomass ... -
Self-organisation of bacteria through swarming
Swarming is a unique example of social behaviour in bacteria. They represent the collective effort of bacteria to translocate on moist substrates. The bacteria extract fluid from the substrate through osmosis and produces ... -
Solution NMR Studies Of E.Coli Acetohydroxy Acid Synthase (AHAS) I
(2010-04-13)Branched chain amino acids are classified as essential amino acids since their biosynthetic routes or pathways are restricted only to micro-organisms, fungi and plants. Given their unique distribution, the enzymes of the ... -
Structural and functional characterization of a bacterial TenpIN type III toxin-antitoxin system and its potential as an antibacterial strategy
Bacterial type III toxin-antitoxin (TA) systems were first identified as abortive infection systems wherein a phage infection causes altruistic suicide of the bacterium to prevent bacteriophage spread among its clonal ... -
Studies on the roles of Lon protease and its substrates during antibiotic resistance in Escherichia coli: modulatory effects of nitroaromatics and nitrofurantoin
Bacteria adapt to environmental stresses, including antibiotic stress, by regulating various genes and metabolic pathways. In prokaryotes, the energy-dependent protein degradation is controlled primarily by two ...