Browsing by Advisor "Varshney,Umesh"
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Importance of formylation in eubacterial translation initiation
Initiation of protein synthesis in all organisms occurs with the amino acid methionine. In the case of eubacteria and eukaryotic organelles, methionine is further modified to formylmethionine by the enzyme methionyl?tRNA ... -
Mechanistic studies on uracil DNA glycosylases from escherichia coli and mycobacteria : Interaction with uracil containing DNA, Single Stranded DNA Binding protiens(SSBs) and an Inhibitor protein(Ugi)
Mutational and Biochemical Analyses of Uracil-DNA Glycosylase (UDG), Single-Stranded DNA Binding Proteins (SSB), and Ugi Abstract and Synopsis Introduction Uracils arise in DNA either by spontaneous deamination of cytosine ... -
Use of formylation defective initiator tRNAs in the study of significance of formylation in initiation of protein synthesis in Escherichia coli
Initiation of protein synthesis is the major regulatory step in the translation of a messenger RNA. Initiation occurs with formylmethionine in eubacteria as opposed to methionine in archaea and eukaryotes. However, the ...