Browsing by Advisor "Varma, Manoj M"
Now showing items 1-20 of 20
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Advanced Multifunctional Bulk Optical & Fiber Bragg Grating Sensing Techniques
(2017-05-04)In this thesis work, a systematic quantitative study has been undertaken, on the performance of etched fiber Bragg Grating (FBG) sensors in the investigation of surface molecular adsorption in real-time; it is shown that ... -
Advances in Microfluidic Impedance Cytometry for Electromechanical Characterization of Cells
Single-cell analysis is extremely important for discovering unique characteristics of individual cells, identifying cell populations of interest, and understanding their behaviour during disease conditions. With the advent ... -
Aptamer-based approaches for multiplexed sensing applications
Biosensors offer high specificity, sensitivity, real-time recognition, and rapid response across various applications, including Medical Diagnostics, Environmental Monitoring, Food Safety, agriculture, Point-of-Care ... -
Bright-field Nanoscopy
This thesis discusses the design and development of a technique which focuses on visualization of nanoscale structures using a regular bright-field optical microscope without the need of any additional fluorescent tags. ... -
Caenorhabditis elegans-Bacteria interactions: Neuronal Regulation of Innate Immune Responses
The survival of an organism depends on its ability to sense threats and execute appropriate defense mechanisms. C. elegans is a soil-dwelling nematode that feeds on bacteria in rotting vegetation. The nematode has few ... -
Development Of Fluorescent OLED And Analysis Of Integrated Optofluidic Lab-on-a Chip Sensor
(2014-04-15)Optofluidics is a new branch within photonics which attempts to unify concepts from optics and microfluidics. Unification of photonics and microfluidics enable us to carry out analysis of fluids through highly sensitive ... -
Fabricating Physical and Robotic Systems to Investigate Collective Behavior
The motion of particles has always been fascinating for scientists. We, as scientists, try to decode the mysteries of motion of massive objects like black holes, stars, and planets to objects nearly void of mass such as ... -
Fabrication and Characterization of Optomechanical Devices
Silicon photonics is a promising platform for photonic devices and circuits, largely driven by advanced complementary metal-oxide-semiconductor (CMOS) processing technology. An extremely crucial component for a photonic ... -
Modelling capture efficiency of microbots
Micro-robotics is one of the fast-growing research domains in the interdisciplinary field of cyber-physical systems. They have immense potential in a plethora of applications like targeted medicine, environmental remediation, ... -
Molecular Dynamics Investigations of Hybrid Nanopores for Single Molecule DNA Sequencing
High throughput methods accelerate the drug discovery, biomolecule detection and sequencing applications pipeline. Single molecule detection technique facilitates the implementation of high throughput methods by eliminating ... -
Molecular Transport in Polyelectrolyte Multilayers
(2018-06-26)Layer-by-layer assembly of polyelectrolytes is a simple technique based on the self-assembly of polycations and polyanions mainly by electrostatic interactions, which has gained considerable scientific interest for its ... -
Multiplexing Nanoplasmonic Sensors
Complex biological samples such as serum contain thousands of proteins and other molecules spanning up to 13 orders of magnitude in concentration. Present measurement techniques such as protein microarrays and quantum dot ... -
Nanopore Based Single-molecule Sensors
In the past two decades nanopores have been used as highly sensitive detection systems for exploring the properties of analytes at single molecule resolution. The small dimensions of a nanopore permit the molecule of ... -
Robust Fabrication Methods for Solid-state Nanopores
Solid-state nanopores represent a versatile and robust technology for high-precision single-molecule detection, offering distinct advantages over biological nanopores in terms of durability, size control, and integration ... -
Self-organisation of bacteria through swarming
Swarming is a unique example of social behaviour in bacteria. They represent the collective effort of bacteria to translocate on moist substrates. The bacteria extract fluid from the substrate through osmosis and produces ... -
Self-referencing Techniques in Optical Label-free Bio-molecular Sensing
Measurement of molecular interactions is essential for fundamental biological studies as well as for the development of health diagnostics devices. Several label-free and labeled techniques to characterize and quantify ... -
Statistical Inference in Biological and Diagnostic Systems
Biological systems are exceptionally good at sensing their environment with extraordinary precision. Certain single cellular organisms are even capable of detecting chemicals of the order of a single molecule. To achieve ... -
Substrate Independent Non-covalent Based Surface Functionalization Using Poyelectrolyte Multilayers for Bio-applications
(2018-04-23)The electrostatic layer-by-layer (LbL) self-assembly of polyelectrolyte’s has shown applications in thin film coatings, micro patterning, nano-bioreactors and capsules for drug delivery. The film architecture can be precisely ... -
Transport in Interfacial Systems: Biosensor, Polymer, Colloid & Bacteria
Life forms as we know emerged due to unique mechanical and transport properties exhibited by Soft Materials at interface. For instance, the interior of a cell is separated from outside environment by lipid bilayer which ... -
Versatile sensing platform using silicon photonic microring resonators
Measurement of refractive indices of liquids and thin films can play an important role for chemical analysis in the fields of healthcare and biomedical research. There is a requirement of miniaturized refractive index ...