Browsing by Advisor "Umapathy, Siva"
Now showing items 1-19 of 19
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Development and Applications of Portable Raman Spectroscopy Combined with Artificial Intelligence for Biomedicine
Currently, the global spectroscopic community is investigating the suitability of vibrational spectroscopy methods for point-of-care testing, histopathology, and rapid in-vivo biomedical diagnostics. Although Raman ... -
Development of Nanosensors and Microfluidics towards Raman Spectroscopic Applications
Surface Enhanced Raman Spectroscopy (SERS) has become a powerful method for detection of diverse analytes ranging from solution of picomolar concentration to single molecule and single cell analysis. The distinctive nature ... -
Elucidating Intricate Excited-state Dynamics in Molecular Systems Using Time-resolved Transient Absorption and Ultrafast Raman Spectroscopy
Abstract The excited-state dynamics of molecular materials is of great importance to understand early time photodynamics. We have used Femtosecond Transient Absorption (fs-TA) and Ultrafast Raman Loss Spectroscopy (URLS) ... -
Excited State Intramolecular Charge Transfer: Ultrafast Electronic and Vibrational Spectroscopic Study
This thesis incorporates the understanding of the ultrafast excited state photoinduced intramolecular charge transfer (ICT) process in liquid phase. The molecular systems are studied by employing Ultrafast Raman Loss ... -
Identifying Bacterial Species, Detecting Antibiotic Resistance and Susceptibilities in Clinical Samples Using Raman Spectroscopy
Over the past few decades, Raman spectroscopy has found enormous applications in biology and medicine. Raman micro-spectroscopy is highly sensitive to the structure and composition of molecules and their surrounding moieties ... -
Investigation of Microbes and Blood Plasma Towards Implications in Biomedicine: A Raman Spectroscopic Study
Raman spectroscopy, combined with artificial intelligence, is becoming increasingly popular in biology because of its sensitivity to molecular changes. This thesis discuss the applications of Raman spectroscopy in analysing ... -
Micro-spectroscopic studies on Mycobacteria & Cancer cells
Evasion of the immune system is a key hallmark of cancer progression. Developing strategies that diagnose early the immune-cancer synapse may lead to long term cures from these aggressive cancers. We aimed to develop optical ... -
Raman and IR Spectroscopic Studies of Bacteria, Endotoxin, DNA and Lipoproteins
In the past few decades, vibrational spectroscopy has emerged as a powerful technique in biomedical research. Raman and IR spectroscopy, which are based on signatures specific to molecular vibrations, has found a wide ... -
Raman Microspectroscopic Studies on Differentiating Bacteria, Detecting Antimicrobial Resistance and Delineating Biomarkers of Sepsis
Over the last few decades, the development of several new techniques as well as sophisticated instruments have contributed to a better understanding of biological systems. Among these, Raman spectroscopy has emerged as an ... -
Raman Spectroscopy Instrumentation and Its Application in Deep Tissue Imaging
Raman spectroscopy is based on inelastic scattering, which gives molecular information. Due to its weak nature, for a long-time Raman spectroscopy was limited to only study of molecular interactions, but with the advancement ... -
Solvent Effects on Photochemistry and Photophysics of Aromatic Carbonyls : A Raman and Computational study
(2017-12-16)Solvent effects play diverse roles in myriads of chemical, physical and biological processes. The solvent interacts with the solute by: i) non-specific (Coulombic, van der Waals interactions) and ii) specific interactions ... -
Structural and Solvent Effects on Excited State Dynamics of Rhenium(I) Tricarbonyl α-Diimine Complexes: A Time-Resolved Spectroscopic and Computational Study
The nature of the lowest excited state in rhenium(I) complex with 1,10-phenathroline as ligand was first reported by Mark Wrighton and David. L. Morse. Since then many rhenium(I) complexes with different ligands having ... -
Ultrafast Raman Loss Spectroscopic Investigations of Excited State Structural Dynamics of Bis(phenylethynyl)benzene and trans-Stilbene
(2018-05-25)The subject of this thesis is the design and development of a unified set up for femtosecond transient absorption and ultrafast Raman loss spectroscopy and demonstrate its potential in capturing the ultrafast photophysical ... -
Ultrafast Raman Loss Spectroscopy (URLS)
(2015-02-05)Contemporary laser research involves the development of spectroscopic techniques to understand the microscopic structural aspects of a simple molecular system in chemical and materials to more complex biological systems ... -
Ultrafast Raman Loss Spectroscopy (URLS) : Understanding Resonant Excitation Response And Linewidth Changes
(2016-02-25)Raman spectroscopy involves change in the polarizability of the molecular system on excitation and is based on scattering process. Spontaneous Raman scattering is a two photon process, in which the input light initiates ... -
Understanding Solvent Effect On Triplet State Structure Of Thioxanthone And Its Derivatives Using Time-Resolved Resonance Raman Spectroscopy
(2014-05-01)It has long been recognized that course and efficiency of a chemical reaction is largely mediated by the short-lived transient species (excited state or radicals) which are formed as reactive intermediates during a chemical ... -
Understanding Ultrafast Molecular Structural Dynamics in Liquids : Ultrafast Raman Loss and Transient Absorption Study
The present thesis deals with the detailed ultrafast experimental studies on the ex-cited state vibrational dynamics of model chemical systems in condensed phase. The molecular systems are studied by means of Ultrafast ... -
Vibrational Microspectroscopic Studies of Biomedical Conditions Using Model Systems
(2018-05-08)Over the last century, despite enormous advancements in biomedical research and the development of sophisticated analytical instruments many diseases continue to be a burden on humankind particularly on the aged. This is ... -
Vibrational Spectroscopic studies of Dynamics of BSA unfolding, Lysozyme-Ethanol interaction and Tissue Imaging
Vibrational spectroscopy has served as a powerful tool for understanding various structural properties of the molecules since decades. In the recent years, it has also emerged as an invaluable tool in understanding various ...