Browsing by Advisor "Samuelson, A G"
Now showing items 1-18 of 18
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Ancillary Ligand Effects On The Anticancer Activity Of Ruthenium(II) Piano Stool Complexes
(2011-01-17)The thesis “Ancillary Ligand Effects on the Anticancer Activity of Ruthenium (II) Piano Stool Complexes” is an effort to design better antitumor metallodrugs based on ruthenium(II) complexes with various H-bond donor/acceptor ... -
Catalytic Studies with Ru and Ir Half-sandwich Complexes Bearing NHC Ligands
The thesis describes the study of arene-tethered and untethered Ru half-sandwich complexes as catalysts in the addition of hydroelements (E‒H, E = H, B, Si) across unsaturated C-C, C-N and C-O bonds and transfer hydrogenation ... -
Chiral Bisphosphinites For Asymmetric Catalysis
(2010-07-21)Chiral bisphosphinites are well-documented alternatives for chiral bisphosphines as ligands that can be exploited in various asymmpetric syntheses. Particularly, vicinal biarylphophinite ligands give a seven membered chelate ... -
A Computational Study of C-H Binding, C-H Activation and Fluxional Processes of d6 Half- Sandwich Complexes
(2017-11-24)Significant developments have been made in the field of C–H activation. However, various disadvantages, mainly low reactivity and selectivity, limit their usage in large-scale synthesis. It is crucial to understand the ... -
Computational Study of General Relationships in Chemistry: C−C, C−N, and B−B Coupling, B−B Catenation, and 2D Metal Borides
Elements in the periodic table are categorized into four major blocks, main group (MG) elements, transition metals (TM), lanthanides (Ln), and actinides (An), which differ dramatically. Recent studies revealed some interesting ... -
A Computational Study Of Nucleophilic Attacks In Organometallic Complexes
(2012-04-23)A wide variety of computational methods are available for exploring molecular structures and reactivity in chemistry. These range from molecular mechanics calculations allowing determination of the geometry of a molecule ... -
Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles
(2018-02-21)Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world. However there is a ... -
Mechanistic Investigation of Metal Promoted Nucleophilic Additions
(2017-11-30)Nucleophilic additions are an important class of reactions in the preparation of several organic compounds. Metals facilitate nucleophilic additions in many cases. The present work Mechanistic Investigation of Metal Promoted ... -
Mechanistic Studies of Transfer Hydrogenation Catalyzed by Ru(ll)-Half-Sandwich and Group 6 NHC complexes
The thesis explores the mechanistic aspects of transfer hydrogenation of ketones and hydrosilylation of imines; two commonly used organic transformations catalyzed by ruthenium half-sandwich complexes of 2-oxazolidinethiones, ... -
Molecularly Imprinted Polymers Based On Fluorescent And Template Binding Cross-Linker
(2013-05-23)The synthesis of materials with molecular recognition properties has become a topic of great technological and scientific interest. Molecular imprinting is one of the most effective strategies in preparing highly selective ... -
Reductive And Metathetic Coupling Reactions Mediated By Group (IV) Metal Alkoxides
(2010-10-19)Several organic transformations are mediated by group(IV) metal alkoxides. The reactivity is based on the basic nature of alkoxide group, Lewis acidic nature of the group(IV) metals, insertion of unsaturated molecules into ... -
Targeted Delivery of Cytotoxic Metal Complexes into Cancer Cells with and without Macromolecular Vehicles
(2018-04-12)Anticancer active metal complexes such as cisplatin are routinely used for treating various cancers since 1978. However, the side effects of cisplatin overwhelm its therapeutic potential, especially in the latter stages ... -
Targeting Cancer Cells And Live Cell Imaging Using Bis(thiosemicarbazone) Complexes Of Copper And Zinc
(2016-02-25)Transition metal bis(thiosemicarbazone) complexes have been of great interest in the last five decades. One of the most striking features of these complexes is that they possess a wide range of biological properties including ...