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    Browsing by Advisor "Eswarappa, Sandeep M"

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      • Hominini-specific regulation of cell cycle by stop codon readthrough of FEM1B 

        Akhtar, Md Noor
        In certain mRNAs ribosomes continue translation beyond the canonical stop codon to generate longer isoform with a C-terminal extension. This phenomenon is termed stop codon readthrough (SCR). Previously, a genome-wide ...
      • Stop codon readthrough in MTCH2 mRNA and its role in mitochondrial physiology 

        Lekha, E M
        Stop codon readthrough is the process in which translation continues beyond a stop codon till a downstream, in-frame stop codon generating a polypeptide with a C-terminal extension. MTCH2 was selected as a potential ...
      • Stop codon readthrough of NNAT mRNA and its role in neuronal differentiation 

        Pandit, Madhuparna
        Protein synthesis terminates at the first stop codon encountered by the ribosome. In stop codon readthrough, translation termination is suppressed, enabling the ribosomes to continue translation beyond the canonical stop ...
      • Translation in Erythroid cells 

        Kumar, Sangeetha Devi
        Erythrocytes are specialized cells that perform the crucial function of gas exchange in all vertebrates. Regulation of gene expression was believed to be absent in these cells due to the absence of nucleus. It was also ...
      • Translation in the 3'Untranslated Region of Mammalian Transcripts 

        Kar, Debaleena
        Mammalian mRNAs generally have a 5'UTR (untranslated region), a coding DNA sequence, and a 3'UTR. The 3'UTR of mRNA is generally believed to be the untranslated region of the mRNA. However, there are certain instances ...
      • Translational readthrough of AGO1 mRNA and its regulation by let-7a microRNA 

        Singh, Anumeha
        During translation, the message encoded in mRNAs is decoded by ribosomes to synthesize proteins following strict canonical decoding rules. This process is tightly regulated and several mechanisms exist in cells that ensure ...

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