Browsing by thesis submitted date"2018"
Now showing items 241-260 of 420
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Modeling and Adaptive Scheduling Strategies for Distributed Graph Algorithms
Graph processing at scales of millions-billions of vertices and edges has become common to solve real-world problems in domains like social networks, smart cities and genomics. Distributed "Big Data" platforms for graph ... -
Modelling and Experimental Studies on Dynamic Behaviour of Electrochemical Double Layer Capacitors
lectrochemical double layer capacitors (EDLCs) can store and deliver electrical energy at high power density with long cycle life, and can absorb peak charge/discharge loads. EDLCs can be used with batteries to insulate ... -
Modelling and optimization of novel therapies for HIV and hepatitis C virus infections
Curing infections by HIV and hepatitis C virus (HCV) have remained a challenge for a long time due to their efficient ways of evading host immune responses and therapies. They do so by rapidly mutating their genomes, which ... -
Modified-graphene and carbon nanodots for nitrogen dioxide sensing: Effects of interfacial electronic modulation and dimensionality on gas interaction
Currently, there is an enormous demand for the development of high performance nitrogen dioxide (NO2) gas sensors for environmental pollution monitoring. Hence, there is a constant quest to replace traditional metal oxide ... -
Modulation of Power Electronic Converter Fed Split-phase Induction Machine Drive
Induction machine (IM) is the workhorse of several industries due to its low cost and minimal maintenance. Power electronic converters play a major role in driving IMs which give better flexibility in these applications. ... -
The Molecular Basis for the Differential Antibiotic Susceptibility of Mycobacterial Subpopulations
Mycobacterial populations have evolved various strategies to withstand diverse stress conditions in the environment. One among these strategies is maintenance of phenotypic heterogeneity, in terms of cell morphology, ... -
Molecular Characterization of Mannose Binding Lectins
Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ... -
Molecular Construction Using Carbene and Diboron Systems: Catalytic Transformation of C-C and C-Hetero Atom Bonds
The thesis presents an unconventional approach for the molecular construction using carbenes as the carbon source, and water as the hydrogen source. A gold-catalyst has been used to transfer the carbenes to effect ... -
Molecular determinants of self-assembly of the pore forming toxin Cytolysin A
Pore forming toxins (PFTs) belong to a class of bacterial exotoxins that disrupt the biological membrane barrier by formation of nanopores. These toxins are central to the virulence of pathogens such as S. pneumoniae, ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Molecular Dynamics Studies of Diffusion in Confined Regions
Diffusion of guest molecules under confinement of zeolites shows many interesting properties due to guest-host interactions. This thesis explores some of these interesting behaviours relating to the diffusion of guest ... -
Molecular insights into AMP-activated protein kinase (AMPK)-mediated regulation of anoikis resistance
Our study identifies negative cross-talk between AMPK and two important cellular kinases, Akt and Erk. AMPK-mediated inhibition of these two kinases promotes survival of cancer cells in the matrix-deprived condition. ... -
Molecular Simulation Studies of Competing Pathways in Crystal Nucleation
Microscopic nature of nuclei and extremely fast nucleation events makes it difficult to study nucleation experimentally. Route to nucleation can be effected by different parameters such as thermodynamic conditions, uid ... -
A molecular systems approach to unravel mechanisms and targets in antifolate-resistant bacteria and cancers
Antifolates such as trimethoprim (TMP) and methotrexate (MTX) widely used for treating bacterial infections and certain cancers respectively, inhibit dihydrofolate reductase (DHFR) in the folate pathway. However, the use ... -
Motion Space Analysis of Smooth Objects in Point Contacts
(2018-07-19)The present work studies instantaneous motion of smooth planar and spatial objects in unilateral point contacts. The traditional first-order instantaneous kinematic analysis is found insufficient to explain many common ... -
Multi-faceted modular interactions in proteins
All living systems are composed of plethora of biomolecules. There are various types of biomolecules such as proteins, DNA, RNA, carbohydrates and metabolites. All the reactions in a biological system involve interactions ... -
Multi-Scale Modeling of Moist Convection Over India
Clouds exist on all scales from turbulent processes to global scale and are organized on all the scales in between. They truly are multi-scale in nature. This makes them a very challenging simulation problem for atmospheric ... -
Multiplexing Nanoplasmonic Sensors
Complex biological samples such as serum contain thousands of proteins and other molecules spanning up to 13 orders of magnitude in concentration. Present measurement techniques such as protein microarrays and quantum dot ... -
Multiview Registration Using Rank-Constrained Semide nite Programming
We consider the problem of reconstructing a 3D surface from its multiview scans. Typically, the computational pipeline for this problem has two phases: (I) finding point-to-point correspondences between overlapping scans, ...