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Structural Studies On Mycobacterial RecA And RuvA
(2010-10-21)
Homologous recombination is a fundamental cellular process evolved to maintain genomic integrity and to generate genetic diversity. It plays a crucial role in DNA repair, correct segregation of meiotic chromosomes and ...
Structural And Functional Analysis Of Proteins With The Double Stranded β-helix (Cupin) Domains
(2010-12-24)
Proteins performing catalytic roles predominantly occur in a few protein folds. Functional diversity within a common structural scaffold has been attributed to conformational features that enable exploration of reaction ...
Probing the Role of Highly Conserved Residues in Triosephosphate Isomerase : Biochemical & Structural Investigations
(2018-05-23)
Conserved residues in protein are crucial for maintaining structure and function, either by direct involvement in chemistry or indirectly, by being essential for folding, stability and oligomerisation and are mostly clustered ...
Intrinsic Versus Induced Variations In DNA Structure
(2011-07-18)
The binding of different proteins involved in processes such as transcription, replication and chromatin compaction to regions of the genome is regulated by the structure of DNA. Thus, DNA structure acts as the crucial ...
Studies On Sesbania Mosaic Virus Asssembly And Structure And Function Of A Survival Protein (SurE) From Salmonella Typhimurium
(2011-03-29)
X-ray crystallography is a powerful method for determining the three-dimensional structures of biological macromolecules at atomic resolution. Crystallography can reliably provide the answer to many structure related ...
Structural And Functional Studies On Staphylococcus Aureus Enzymes Involved In L-Lysine Biosynthesis
(2011-05-24)
Proteins associated with metabolic pathways have received considerable attention in an effort to understand the molecular details of the complex reactions catalyzed in vivo. Enzymes belonging to these pathways have also ...