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Non-repetitive Structures In Proteins : Effects Of Side-chain And Solvent Interactions With The Backbone
(Indian Institute of Science, 2006-05-12)
The work presented in this thesis deals with the analysis of protein crystal structures with an emphasis on the stereochemical aspects of the folded conformation of proteins. The various analyses described have been performed ...
Starvation Response In Mycobacterium Smegmatis : A Tale Of Two Proteins
(2010-10-19)
The Dps (DNA-Binding Protein from Starved Cells) proteins are a class of stress-specific proteins with a major role in protecting DNA during the stationary phase of bacterial growth, through direct physical binding as well ...
Energetics Of Protein-Carbohydrate Recognition
(Indian Institute of Science, 2006-04-28)
The work embodied in this thesis pertains to an attempt to understand better, the molecular basis of protein-carbohydrate recognition. For this purpose a systematic study was undertaken, not only of the energetics of ...
Thermodynamic Characterization Of Wild Type And Mutants Of The E.coli Periplasmic Binding Proteins LBP, LIVBP, MBP And RBP
(2009-03-13)
Native states of globular proteins typically show stabilization in the range of 5 to
15 kcal/mol with respect to their unfolded states. There has been a considerable progress in the area of protein stability and folding ...
Computational Analyses Of Proteins Encoded In Genomes Of Pathogenic Organisms : Inferences On Structures, Functions And Interactions
(2015-02-04)
The availability of completely sequenced genomes for a number of organisms provides an opportunity to understand the molecular basis of physiology, metabolism, regulation and evolution of these organisms. Significant ...
Structure Analysis Of Plant Lectin Domains
(2014-04-07)
Lectins are multivalent carbohydrate binding proteins that specifically recognise diverse sugar structures and mediate a variety of biological processes, such as cell-cell and host-pathogen interactions, serum glycoprotein ...
Mechanism Of Anticancer And Antimalarial Action Of A Modulator Of Heat Shock Proteins
(2007-11-16)
This thesis entitled “Mechanism of Anticancer and Antimalarial Action of
a Modulator of Heat Shock Proteins” describes the successful elucidation of the
mechanism of anticancer and antimalarial action of 15-Deoxyspergualin ...