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X-ray Crystallographic Characterization Of Designed Peptides Containing Heterochiral And Homochiral Diproline Segments And Database Analysis
(2010-12-30)
Understanding the relation between amino acid sequences and protein structures is one of the most important problems in modern molecular biology. However, due to the complexities in the protein structure, this task is ...
Studies Of Spiral Turbulence And Its Control In Models Of Cardiac Tissue
(2010-07-15)
There is a growing consensus that life-threatening cardiac arrhythmias like ventricular tachycardia (VT) or ventricular fibrillation (VF) arise because of the formation of spiral waves of electrical activation in cardiac ...
Structure and Dynamics of Interfacial Molecular Membranes
(2018-04-16)
This thesis describes the study on structure and dynamics of various kinds of molecular membranes in general. We have studied the morphological transition of colloidal as well as biologically relevant membranes and ...
Development And Optimization Of A Microchip PCR System Using Fluorescence Detection
(2011-02-21)
Microfabricated thermal cyclers for nucleic acid amplification by using polymerase chain reaction (PCR) have been demonstrated by several groups over the last decade, with improved cycling speed and smaller volumes when ...
X-Ray Crystallograhic Studies On 2',5', Cyclic And Modified Nucleotides
(2007-09-05)
This thesis presents the crystal structures of 2', 5', cyclic and modified nucleosides / nucleotides. Chapter I gives a brief account of the structural studies on 2', 5' and modified nucleotides. It also presents a short, ...
Crystal Structure Of Abrus Precatorius Agglutinin-I (APA-I) : Insights Into The Reduced Toxicity Of APA-I In Relation To Abrin. Formation Of Ordered Nanotubes Through Self Assembly In The Crystal Structures Of Dipeptides Containing α. β-dehydrophenylalanine
(2009-07-22)
Ribosome Inactivating Proteins (RIPs) are protein or glycoprotein toxins that bring about the arrest of protein synthesis by directly interacting with and inactivating the ribosomes. Such toxins are in general, of plant ...
Optical Tweezers and Its use in Studying Red Blood Cells - Healthy and Infected
(2017-11-29)
The experiment discussed in the next chapter was to confirm the aforementioned bystander effect. In the first experiment we separated hosting and non-hosting mRBCs by the percol purification method and then measured the corner ...
Thermal Fluctuation Spectroscopy And Its Application In The Study Of Biomolecules
(2009-03-03)
The aim of this thesis is to study the energy fluctuations (leading to thermal fluctuations) during thermal and enzymatic denaturation of biological molecules and to study the variation in fluctuations between simple ...
Spiral-Wave Dynamics in Ionically Realistic Mathematical Models for Human Ventricular Tissue
(2018-04-18)
There is a growing consensus that life-threatening cardiac arrhythmias like ven- tricular tachycardia (VT) or ventricular fibrillation (VF) arise because of the formation of spiral waves of electrical activation in cardiac ...