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dc.contributor.advisorPrabhu, K R
dc.contributor.authorHande, Akshay
dc.date.accessioned2020-08-13T05:27:56Z
dc.date.available2020-08-13T05:27:56Z
dc.date.submitted2019
dc.identifier.urihttp://etd.iisc.ac.in/handle/2005/4532
dc.description.abstractThe thesis represents an approach for the C-H bond activation using directing group strategy. The C-H activation happens through five/six-membered metallacycle through concerted metallation deprotonation. Further functionalization leads to C-N formation in the presence of an amidating reagent dioxazolone. Dioxazolone a robust and efficient amidating reagent has been utilized for the C-N bond formation reaction. The strategy has been applied for the azobenzene derivatives for further benzotriazole heterocycle synthesis. The 7-amino indoline derivatives have been synthesized at the ambient condition which endures an application in bioactive molecules. Subsequently, the amidated 2-amido aldehydes and ketones derivatives have been utilized for the synthesis of quindolinone alkaloidsen_US
dc.language.isoen_USen_US
dc.rightsI grant Indian Institute of Science the right to archive and to make available my thesis or dissertation in whole or in part in all forms of media, now hereafter known. I retain all proprietary rights, such as patent rights. I also retain the right to use in future works (such as articles or books) all or part of this thesis or dissertationen_US
dc.subjectIndoline, aldehyde and C-H activationen_US
dc.subjectIndolineen_US
dc.subjectaldehydeen_US
dc.subjectC-H activationen_US
dc.subject.classificationResearch Subject Categories::CHEMICAL SCIENCESen_US
dc.titleRegioselective C-H Amidation Reactions using Directing Group Strategy and its Application in Organic Synthesisen_US
dc.typeThesisen_US
dc.degree.namePhDen_US
dc.degree.levelDoctoralen_US
dc.degree.grantorIndian Institute of Scienceen_US
dc.degree.disciplineFaculty of Scienceen_US


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