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Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the
primary cellular barrier against the extracellular environment. The high-density of embedded
proteins and glycosylated molecules ...
Paper microfluidic tools to improve the sensitivity and dynamic range of point-of-care immunoassays
Over the past decade, developing affordable home-based tests to diagnose infectious diseases has become a pressing need. The lateral flow immunoassay (LFIA) is the most successfully commercialized point-of-care immunoassay. ...
Inkjet-Printed Ag Nanomaterials based Strain Sensors for Wearable Sensing Applications
Of late, the demand of wearable sensors has exponentially risen. For example, strain sensors that can be worn and are skin mountable play a significant role in the areas of human motion detection, healthcare, soft robotics, ...
Refractive-Index-Matched Fluorescent Particle Image Velocimetry for Investigation of Flow in Immersed Granular Materials
Refractive-Index-Matched Fluorescent Particle Image Velocimetry for Investigation of Flow in Immersed Granular Materials
The ubiquity of granular materials and their importance in everyday life, industry, and nature make ...
Translation from batch to continuous processing of metal nanoparticle synthesis and application metallic nanostructures printed on flexible substrates
One of the key challenges in nanoparticle synthesis is the quality control on scaling up
the operation from bench to plant scale, which is constrained by conventionally adopted
batch operation. Translation from batch ...
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich
membranes through atomistic molecular dynamics simulations. The PFT of interest
is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ...
Development of noble metal catalysts and detailed kinetic models for CO oxidation and water gas shift reactions
Noble metal (Pt, Pd, Rh) based catalysts have been highly effective for CO abatement applications such as CO oxidation and the water gas shift reaction (WGS). In the venture for development of novel catalysts, noble metal ...
Flow and structure of dense granular materials
Granular materials are frequently encountered in our daily lives and are widely processed forms
of matter in various industries. Despite decades of research, the mechanical behavior of
granular materials is not well ...
Processing mediated polymorphism in PVDF-based dielectric polymers and their application
The ever-increasing demand in electronic devices, piezoelectric materials such as ceramics,
polymers and polymer ceramic composites with enhanced piezoelectric and dielectric properties
has become the focus of many ...
DNA-based fluorescent reporters for biosensing and lipid dynamics
With the growth of DNA nanotechnology, significant efforts have been made to expand the chemical functionality of DNA beyond the genetic code carrier. By leveraging the specificity of the interactions and modularity afforded, ...