Browsing Chemical Engineering (CE) by Advisor "Toley, Bhushan J"
Now showing items 1-5 of 5
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Advancements in Nucleic Acid Lateral Flow Assay
In recent decades, the demand for rapid and precise nucleic acid amplification tests (NAATs) has grown significantly, driven by the need to address pandemics like COVID-19 and diagnose infectious diseases such as ... -
FLIPP-NAAT: A paper-based LAMP assay for point-of-care TB detection
Molecular diagnostic techniques like polymerase chain reaction (PCR) revolutionized the world of healthcare. Instead of waiting for infectious agents to physically grow as in conventional culture-based tests, genetic ... -
Novel Microfluidic Tools for Multiplex Colorimetric Detection of Analytes and Point Mutation Detection in Infectious Pathogens
Recently, the need for affordable point-of-care tests has grown exponentially. An ideal point of care (POC) test or device should satisfy the WHO-endorsed ASSURED criteria, meaning that the test/device should be accessible, ... -
Paper microfluidic tools to improve the sensitivity and dynamic range of point-of-care immunoassays
Over the past decade, developing affordable home-based tests to diagnose infectious diseases has become a pressing need. The lateral flow immunoassay (LFIA) is the most successfully commercialized point-of-care immunoassay. ... -
Paper-Based Point-of-Care Diagnostic Tools: Electrokinetic Nucleic Acid Extraction and Saliva-Based Glucose Detection for Diabetes Monitoring
Currently, we face a global challenge posed by the dual burden of chronic diseases such as diabetes and infectious diseases such as tuberculosis (TB). Low-and middle-income countries are disproportionately overburdened by ...