Browsing Chemical Engineering (CE) by Advisor "Roy, Rahul"
Now showing items 1-5 of 5
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DNA-based fluorescent reporters for biosensing and lipid dynamics
With the growth of DNA nanotechnology, significant efforts have been made to expand the chemical functionality of DNA beyond the genetic code carrier. By leveraging the specificity of the interactions and modularity afforded, ... -
Droplet Isothermal Amplification For Nucleic Acid Quantification
Nucleic acid quantification (NAQ) is extensively employed for gene expression analysis, monitoring viral loads, detecting rare or dysfunctional cells, and assessing treatment regimes. The gold standard, quantitative ... -
Droplet Microfluidics for Nucleic Acid Quantification and Single Cell Analysis
Droplet microfluidics provides controlled generation of monodispersed droplets of the order of a few picoliters in multiphase microfluidic systems. These droplets are employed as micro-reactors to conduct chemical/biochemical ... -
Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the primary cellular barrier against the extracellular environment. The high-density of embedded proteins and glycosylated molecules ... -
Understanding the interplay between immune response and virus evolution
RNA viruses are the underlying cause of many human diseases, including the common cold, influenza, dengue fever, and COVID-19. Their ability to evolve rapidly makes them challenging to tackle, resulting in public health ...