Browsing Chemical Engineering (CE) by Title
Now showing items 62-81 of 138
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Modeling The Population Dynamics Of Erythrocytes To Identify Optimal Drug Dosages For The Treatment Of Hepatitis C Virus Infection
(2016-04-28)The current treatment for hepatitis C virus (HCV) infection – combination therapy with pegylated interferon and ribavirin – elicits sustained responses in only ~50% of the patients treated. Greater cumulative exposure ... -
Modelling and Experimental Studies on Dynamic Behaviour of Electrochemical Double Layer Capacitors
lectrochemical double layer capacitors (EDLCs) can store and deliver electrical energy at high power density with long cycle life, and can absorb peak charge/discharge loads. EDLCs can be used with batteries to insulate ... -
Modelling and optimization of novel therapies for HIV and hepatitis C virus infections
Curing infections by HIV and hepatitis C virus (HCV) have remained a challenge for a long time due to their efficient ways of evading host immune responses and therapies. They do so by rapidly mutating their genomes, which ... -
Modelling How Refractoriness to Interferon Compromises Interferon-Free Treatment of Hepatitis C Virus Infection
(2018-05-25)Hepatitis C virus (HCV) infection globally affects 130-150 million people. It causes both acute and chronic infections. Due to the severe side effects and low success rates of interferon based treatments, which formed the ... -
Modelling Of Precipitation In Reverse Micelles
(Indian Institute of Science, 2005-09-20)Nanoparticles have important applications in ceramics, metal catalysts, semiconductors etc. They are normally required to be of small size (~ nm) and monodisperse. The aim of the present work is to model the formation of ... -
Molecular Analysis of the Pore Forming Mechanism of an α-Helical Cytolysin
Pore forming toxins (PFTs) are lytic membrane binding proteins that are ubiquitous across the animal kingdom and disrupt the structural integrity of the host cell membrane. A unique characteristic of these toxins is that ... -
Molecular dynamics investigations of the bacterial cell envelope: Elucidating differential barriers for antimicrobials
The bacterial cell envelopes possess a complex multilayered architecture exhibiting unique properties evolved to regulate interactions with the external environment and molecules with antimicrobial properties. A molecular ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Molecular Simulation Studies of Competing Pathways in Crystal Nucleation
Microscopic nature of nuclei and extremely fast nucleation events makes it difficult to study nucleation experimentally. Route to nucleation can be effected by different parameters such as thermodynamic conditions, uid ... -
Molecular Simulation Study of Electric Double Layer Capacitor With Aqueous Electrolytes
(2018-05-22)Electric double layer capacitors (EDLCs) are an important class of electrical energy storage devices which store energy in the form of electric double layers. The charging mechanism is highly reversible physical adsorption ... -
Monodisperse Gold Nanoparticles : Synthesis, Self-Assembly and Fabrication of Floating Gate Memory Devices
(2018-04-23)The emergence of novel electronic, optical and magnetic properties in ordered two-dimensional (2D) nanoparticle ensembles, due to collective dipolar interactions of surface plasmons or excitons or magnetic moments have ... -
Monte Carlo simulations of Electric Double Layer Capacitors with aqueous electrolytes
Electric double layer capacitors (EDLCs) also known as supercapacitors are a category of energy storage devices that are known for their remarkable power delivery (upto 1000KW/kg). The energy storage is through physical ... -
Multi-scale Modelling of Lamellar Mesophases
(2018-05-25)Surfactants are amphiphilic molecules which self-assemble at the interface in oil-water-surfactant mixtures such that the hydrophobic part, called tail, stays in oil and the remaining part, called head, resides in hydrophilic ... -
Non-catalytic synthesis of biodiesel and solubilities of mixtures of lipid derivatives in supercritical fluids
The fossil fuels are depleting rapidly as the demand for energy and its allied chemicals is continuously increasing in the modern world. In addition, the concerns over climate change due to the greenhouse gases emitting ... -
Non-catalytic Synthesis of Biolubricant Esters and their Solubilities in Supercritical Fluids
Breakdown products released due to increased loss of mineral oil based lubricants to the environment lead to aquatic toxicity and release of harmful volatile compounds into the atmosphere. The production of these conventional ... -
Novel Microfluidic Tools for Multiplex Colorimetric Detection of Analytes and Point Mutation Detection in Infectious Pathogens
Recently, the need for affordable point-of-care tests has grown exponentially. An ideal point of care (POC) test or device should satisfy the WHO-endorsed ASSURED criteria, meaning that the test/device should be accessible, ... -
Oxygen Transfer In Pichia Pastoris Fermentation
(2009-03-17)Recombinant Pichia pastoris is one of the important methylotropic yeast due to its robustness and ability to produce hormones like human chorionic gonadotropin (hCG), luteinizing hormone (LH) extracellularly. High growth ...